Evidence map›Paper›PMID 34890235›Full record

ArticleScience advances2021

Mechanical oscillations orchestrate axial patterning through Wnt activation in

Jaroslav Ferenc, Panagiotis Papasaikas, Jacqueline Ferralli, Yukio Nakamura, Sebastien Smallwood, Charisios D Tsiairis

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
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  6. Embryonic scaling: morphogen gradients, size sensing, and scaler genes.Frontiers in cell and developmental biology · 2026
    Review
  7. Article
  8. Article
  9. Current zoology · 2025
    Article
  10. Regulation of epithelial tissue homeostasis by active transepithelial transport.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Anisotropic stretch biases the self-organization of actin fibers in multicellular Hydra aggregates.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. IsJournal of developmental biology · 2025
    Review
  13. Article
  14. Article
  15. Topology changes ofScience advances · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Mechanically guided cell fate determination in early development.Cellular and molecular life sciences : CMLS · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jaroslav FerencFriedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.ORCID 0000-0001-5210-3501
Panagiotis PapasaikasFriedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.
Jacqueline FerralliFriedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.
Yukio NakamuraInstitute of Medical Sciences, University of Aberdeen, AB25 2ZD Aberdeen, UK.ORCID 0000-0003-2838-1127
Sebastien SmallwoodFriedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.
Charisios D TsiairisFriedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.ORCID 0000-0002-9788-9875

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanical input shapes cell fate decisions during development and regeneration in many systems, yet the mechanisms of this cross-talk are often unclear. In regenerating

Identifiers

PMID34890235
PMCPMC8664257

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.