Evidence map›Paper›PMID 34890225›Full record

ArticleScience advances2021

Using game theory to thwart multistage privacy intrusions when sharing data.

Zhiyu Wan, Yevgeniy Vorobeychik, Weiyi Xia, Yongtai Liu, Myrna Wooders, Jia Guo, Zhijun Yin, Ellen Wright Clayton, Murat Kantarcioglu, Bradley A Malin

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. HydraGAN: A Cooperative Agent Model for Multi-Objective Data Generation.ACM transactions on intelligent systems and technology · 2024
    Article
  6. Article
  7. Article
  8. Managing re-identification risks while providing access to the All of Us research program.Journal of the American Medical Informatics Association : JAMIA · 2023
    Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhiyu WanDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN 37212, USA.ORCID 0000-0003-3752-5778
Yevgeniy VorobeychikDepartment of Computer Science and Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.ORCID 0000-0003-2471-5345
Weiyi XiaDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37203, USA.ORCID 0000-0003-0406-4944
Yongtai LiuDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN 37212, USA.ORCID 0000-0002-0279-3644
Myrna WoodersDepartment of Economics, Vanderbilt University, Nashville, TN 37235, USA.ORCID 0000-0002-2637-1702
Jia GuoDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN 37212, USA.
Zhijun YinDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN 37212, USA.
Ellen Wright ClaytonCenter for Biomedical Ethics and Society, Vanderbilt University Medical Center, Nashville, TN 37203, USA.ORCID 0000-0002-0308-4110
Murat KantarciogluDepartment of Computer Science, University of Texas at Dallas, Richardson, TX 75080, USA.
Bradley A MalinDepartment of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN 37212, USA.ORCID 0000-0003-3040-5175

Funding

Genetic Privacy and Identity in Community Settings - GetPreCiSeRM1HG009034 · NHGRI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CLAYTON, ELLEN WRIGHT, MALIN, BRADLEY A. · 2016 to 2024
$8.3M
The Electronic Medical Records and Genomics (eMERGE) Network Phase III Coordinating Center (U01)U01HG008701 · NHGRI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PETERSON, JOSEPH F. · 2015 to 2019
$7.1M
A Risk Management Framework for Identifiability in Genomics ResearchR01HG006844 · NHGRI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MALIN, BRADLEY A. · 2012 to 2019
$2.4M
Technologies to Enable Privacy in Biomedical DatabanksR01LM009989 · NLM · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MALIN, BRADLEY A. · 2009 to 2014
$1.6M
NHGRI NIH HHS R01 HG006844NHGRI NIH HHS RM1 HG009034NHGRI NIH HHS U01 HG008701NLM NIH HHS R01 LM009989
6 · The paper itself

Abstract

Person-specific biomedical data are now widely collected, but its sharing raises privacy concerns, specifically about the re-identification of seemingly anonymous records. Formal re-identification risk assessment frameworks can inform decisions about whether and how to share data; current techniques, however, focus on scenarios where the data recipients use only one resource for re-identification purposes. This is a concern because recent attacks show that adversaries can access multiple resources, combining them in a stage-wise manner, to enhance the chance of an attack’s success. In this work, we represent a re-identification game using a two-player Stackelberg game of perfect information, which can be applied to assess risk, and suggest an optimal data sharing strategy based on a privacy-utility tradeoff. We report on experiments with large-scale genomic datasets to show that, using game theoretic models accounting for adversarial capabilities to launch multistage attacks, most data can be effectively shared with low re-identification risk.

Identifiers

PMID34890225
PMCPMC8664254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.