Evidence map›Paper›PMID 34890104›Full record

Trial reportAddiction (Abingdon, England)2022

Efficacy and utilization of an acceptance and commitment therapy-based smartphone application for smoking cessation among Black adults: secondary analysis of the iCanQuit randomized trial.

Margarita Santiago-Torres, Kristin E Mull, Brianna M Sullivan, Diana Kwon, Nicolle L Nollen, Michael J Zvolensky, Jonathan B Bricker

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Addiction (Abingdon, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Characteristics of Black Adults Who Never Achieved 24-Hours of Abstinence in a Smoking Cessation Trial: Implications for Improving Treatment Response.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Trial
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  6. Article
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  11. Review
  12. Mobile Health Interventions for Substance Use Disorders.Annual review of clinical psychology · 2024
    Review
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Margarita Santiago-TorresDivision of Public Health Sciences, Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.ORCID 0000-0001-6051-3172
Kristin E MullDivision of Public Health Sciences, Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Brianna M SullivanDivision of Public Health Sciences, Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Diana KwonDivision of Public Health Sciences, Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Nicolle L NollenDepartment of Preventive Medicine, University of Kansas School of Medicine, Kansas City, KS, USA.ORCID 0000-0002-0943-0061
Michael J ZvolenskyDepartment of Psychology, University of Houston, Houston, TX, USA.
Jonathan B BrickerDivision of Public Health Sciences, Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.ORCID 0000-0002-5694-8795

Funding

Testing a Digital Therapeutic for Smoking Cessation among Hispanic Persons who SmokeU54MD015946 · NIMHD · UNIVERSITY OF HOUSTON · PI Bettina M. Beech · 2020 to 2026
$22.0M
Randomized Trial of an Innovative Smartphone Intervention for Smoking CessationR01CA192849 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BRICKER, JONATHAN B · 2015 to 2019
$3.1M
National Institute on Minority Health and Health Disparities to the University of Houston U54MD015946NCI NIH HHS R01 CA192849NIMHD NIH HHS U54 MD015946
6 · The paper itself

Abstract

BACKGROUND AND

aimsBlack adults who smoke are less likely to seek treatment and to succeed in quitting compared with other racial groups. The lack of efficacious and engaging trials for smoking cessation further contributes to this disparity. This study explored whether an acceptance and commitment therapy (ACT)-based smartphone application (iCanQuit) was more efficacious for smoking cessation than a United States Clinical Practice Guidelines (USCPG)-based smartphone application (QuitGuide) among Black adults.

designSecondary analysis of a two-arm randomized trial with 12-month follow-up.

settingUnited States (US).

participantsA total of 554 Black adults who smoke daily were recruited from 34 US states and enrolled between May 2017 and September 2018.

interventionsParticipants were randomized to receive iCanQuit (n = 274) or QuitGuide (n = 280) for 12 months. MEASUREMENTS: Smoking cessation outcomes were measured at 3, 6, and 12 months. The primary outcome was self-reported complete-case 30-day point prevalence abstinence (PPA) at 12 months. Secondary outcomes were 7-day PPA, missing-as-smoking imputation, multiple imputation, prolonged abstinence, and cessation of all tobacco products at 12 months. Study retention, treatment engagement, and change in ACT-based processes were also compared between arms.

findingsStudy retention was 89% at 12 months and did not differ by arm (P > 0.05). The complete-case 30-day PPA was 28% for iCanQuit versus 20% for QuitGuide at 12 months (odds ratio [OR] = 1.60; 95% confidence interval [CI] = 1.03, 2.46). Similar associations were observed for the missing-as-smoking imputation, although non-significant (25% iCanQuit vs 18% QuitGuide; OR = 1.50; 95% CI = 0.98, 2.30). iCanQuit vs QuitGuide participants were significantly more engaged with iCanQuit application as measured by the number of logins from baseline to 6 months (incidence rate ratio = 3.26; 95% CI = 2.58, 4.13). Increased acceptance of cues to smoke mediated the effect of treatment on cessation (indirect effect: OR = 0.20; 95% CI = 0.05, 0.29).

conclusionsAmong Black adults, an acceptance and commitment therapy-based smartphone application appeared to be more efficacious and engaging for smoking cessation than the United States Clinical Practice Guidelines-based QuitGuide application.

Indexed as

Acceptance and Commitment TherapyMobile ApplicationsSmoking CessationTobacco ProductsAdultHumansSmartphoneAcceptance and commitment therapyblack adultsdigital interventionsiCanQuitsmartphone applicationssmoking cessation

Identifiers

PMID34890104
PMCPMC9798432

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.