Evidence map›Paper›PMID 34890007›Full record

ReviewLa Radiologia medica2022

CT-guided cryoablation for management of bone metastases: a single center experience and review of the literature.

Francesco Arrigoni, Giampaolo Bianchi, Francesco Formiconi, Pierpaolo Palumbo, Luigi Zugaro, Giovanni Luca Gravina, Antonio Barile, Carlo Masciocchi

Abstract readReview
PubMed Publisher
In one paragraph

Review in La Radiologia medica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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  8. Management of metastatic bone disease of the pelvis: current concepts.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Francesco ArrigoniDepartment of Emergency and Interventional Radiology, San Salvatore Hospital, L'Aquila, Italy. arrigoni.francesco@gmail.com.ORCID http://orcid.org/0000-0001-7793-1872
Giampaolo BianchiU.O.C. Radiology and Interventional Radiology, San Filippo E Nicola Hospital, Avezzano, Italy.
Francesco FormiconiDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Pierpaolo PalumboDepartment of Emergency and Interventional Radiology, San Salvatore Hospital, L'Aquila, Italy.ORCID http://orcid.org/0000-0003-1514-0092
Luigi ZugaroDepartment of Emergency and Interventional Radiology, San Salvatore Hospital, L'Aquila, Italy.
Giovanni Luca GravinaDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Antonio BarileDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.ORCID http://orcid.org/0000-0003-0253-3583
Carlo MasciocchiDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.ORCID http://orcid.org/0000-0001-5713-0875
University of L'Aquila · ITSan Salvatore Hospital · ITOspedale San Filippo Neri · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thermal ablation techniques are procedures of growing interest for management of bone metastases. Among these, cryoablation is probably the most advanced. It allows treatment of large and irregular volumes of pathological tissue, real-time evaluation of the area of ablation and appears less painful than heat-based ablative techniques like radiofrequency and microwaves. Literature shows the effectiveness of cryoablation in the management of bone metastases in terms of pain palliation, but also its employment with curative intent is recommended. We reviewed the outcomes of cryoablation procedures performed in our radiology department over the last seven years, confirming the results in terms of pain palliation and local control of disease. We retrospectively evaluated results of 28 procedures of cryoablation, of which 17 treated with palliative and 11 with curative intent. In a 3-month follow-up study, we recorded an overall reduction of pain (evaluated using a VAS 0-10 scale) between pre- and post-treatment. The mean values dropped from 6.9 (SD: ± 1.3) to 3.5 (SD ± 2.6) (p < 0.0001). In the group of patients treated for local tumor control (follow-up: 22.4 months), we recorded a stability and/or reduction in volume of the lesion in 10 out 11 patients. No major complications were recorded.

Indexed as

AdultAgedAged, 80 and overBone NeoplasmsCryosurgeryFemaleFollow-Up StudiesHumansMaleMiddle AgedRadiography, InterventionalRetrospective StudiesTomography, X-Ray ComputedTreatment OutcomeBone metastasisCryoablationInterventional radiologyLocal tumor controlPain palliationThermal ablation

Identifiers

PMID34890007
OpenAlexW4200210970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.