Evidence map›Paper›PMID 34889988›Full record

ArticleApplied microbiology and biotechnology2022

Infection and protection responses of deletion mutants of non-structural proteins of foot-and-mouth disease virus serotype Asia1 in guinea pigs.

H Lalzampuia, Subhadra Elango, Jitendra K Biswal, Narayanan Krishnaswamy, R P Tamil Selvan, P Saravanan, Priyanka Mahadappa, V Umapathi, G R Reddy, V Bhanuprakash and 2 more

Abstract read
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In one paragraph

Article in Applied microbiology and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

H LalzampuiaICAR-NRC On Mithun, Medziphema, Nagaland, India.
Subhadra ElangoFMD Vaccine Production Laboratory, ICAR-Indian Veterinary Research Institute (IVRI), Hebbal Campus, Karnataka, Bengaluru, 560 024, India.
Jitendra K BiswalICAR-Directorate of Foot-and-Mouth Disease, Mukteswar, Nainital, 263138, India.
Narayanan KrishnaswamyFMD Vaccine Production Laboratory, ICAR-Indian Veterinary Research Institute (IVRI), Hebbal Campus, Karnataka, Bengaluru, 560 024, India.
R P Tamil SelvanFMD Vaccine Production Laboratory, ICAR-Indian Veterinary Research Institute (IVRI), Hebbal Campus, Karnataka, Bengaluru, 560 024, India.
P SaravananFMD Vaccine Production Laboratory, ICAR-Indian Veterinary Research Institute (IVRI), Hebbal Campus, Karnataka, Bengaluru, 560 024, India.
Priyanka MahadappaFMD Vaccine Production Laboratory, ICAR-Indian Veterinary Research Institute (IVRI), Hebbal Campus, Karnataka, Bengaluru, 560 024, India.
V UmapathiFMD Q&C and Q&A Laboratory, Bengaluru, India.
G R ReddyFMD Vaccine Production Laboratory, ICAR-Indian Veterinary Research Institute (IVRI), Hebbal Campus, Karnataka, Bengaluru, 560 024, India.
V BhanuprakashFMD Vaccine Production Laboratory, ICAR-Indian Veterinary Research Institute (IVRI), Hebbal Campus, Karnataka, Bengaluru, 560 024, India.
Aniket SanyalFMD Vaccine Production Laboratory, ICAR-Indian Veterinary Research Institute (IVRI), Hebbal Campus, Karnataka, Bengaluru, 560 024, India.
H J DechammaFMD Vaccine Production Laboratory, ICAR-Indian Veterinary Research Institute (IVRI), Hebbal Campus, Karnataka, Bengaluru, 560 024, India. dechamma.j@icar.gov.in.
Indian Veterinary Research Institute · INNational Research Centre on Mithun · INProject Directorate on Foot and Mouth Disease · IN

Funding

indian council of agricultural research CAAST-ACLH (NAHEP/CAAST/2018-19ugc-dae consortium for scientific research, university grants commission UGC- Maulana Azad National Fellowship (Ref No.F1-17.1/2014-15/MANF-2014-15-CHR-MIZ-36717)
6 · The paper itself

Abstract

The development of a negative marker vaccine against the foot-and-mouth disease virus (FMDV) will enhance the capabilities to differentiate vaccinated from infected animals and move forward in the progressive control pathway for the control of FMD. Here, we report the development of mutant FMDV of Asia1 with partial deletion of non-structural proteins 3A and 3B and characterization of their infectivity and protection response in the guinea pig model. The deleted FMDV Asia1/IND/63/1972 mutants, pAsia

Indexed as

Foot-and-Mouth DiseaseFoot-and-Mouth Disease VirusViral VaccinesAnimalsAntibodies, NeutralizingCattleGuinea PigsMiceSerogroupAntibodies, NeutralizingViral VaccinesDeletion mutantsFMDV 3A and 3B proteinsInfectivity

Identifiers

PMID34889988
OpenAlexW4200501199

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.