ReviewApplied microbiology and biotechnology2022
Ligilactobacillus salivarius functionalities, applications, and manufacturing challenges.
Review in Applied microbiology and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed.
- Article
- Current Understanding of Probiotic Strains and Immune Function: From Gut Microbiota to Systemic Immunity.International journal of molecular sciences · 2026Review
- Article
- Feline-DerivedMicroorganisms · 2026Article
- Age-Dependent Alterations in Intestinal Barrier Function: Involvement of Microbiota and TLR4 Signaling.Biology · 2026Article
- Lifestyle associates with unique resistome and microbiome signatures in children.BMC microbiology · 2026Article
- Safety Evaluation of Human-Derived Uric Acid Degrading Lacticaseibacillus paracasei M2a and Its Impact on Gut Microbiota.Probiotics and antimicrobial proteins · 2026Article
- Comparative Evaluation of Spores and Vegetative Forms of Bacillus subtilis and Bacillus licheniformis on Probiotic Functionality In Vitro and In Vivo.Probiotics and antimicrobial proteins · 2025Article
- Autism-Associated Gut Microbiota-DerivedPathogens (Basel, Switzerland) · 2025Article
- Gut Microbiota Provide Co-Existing Strategies for Two Species of Symmetrically Distributed Rodents in Competition for Food.Ecology and evolution · 2025Article
- Biogenic-Synthesized Silver Nanoparticles Using the Ligilactobacillus salivarius KC27L Postbiotic: Antimicrobial, Anti-Biofilm, and Antioxidant Activity and Cytotoxic Effects.Probiotics and antimicrobial proteins · 2025Article
- Dynamic Changes in the Crop Milk and Salivary Microbiota of Breeding Pigeons During the Raising Brooding Period.Animals : an open access journal from MDPI · 2025Article
- Impact of physical parameters on EPS production and gene expression in Ligilactobacillus salivarius KC27L and Limosilactobacillus reuteri KC21L strains.Folia microbiologica · 2025Article
- Investigating the immunomodulatory effects of honeybee venom peptide apamin inInfection and immunity · 2025Article
- Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance.Molecular oncology · 2025Article
- Anxiolytic Effects ofFoods (Basel, Switzerland) · 2025Article
- Dietary bile acid supplementation improves the intestinal health and growth performance of piglets partially through the FXR/AQPs pathway.Porcine health management · 2025Article
- Deciphering the coordinated roles of the host genome, duodenal mucosal genes, and microbiota in regulating complex traits in chickens.Microbiome · 2025Article
- Impact ofFrontiers in nutrition · 2025Article
- Complete genome sequence, metabolic profiling and functional studies revealFrontiers in microbiology · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Ligilactobacillus salivarius is a lactic acid bacteria that has been gaining attention as a promising probiotic. Numerous strains exhibit functional properties with health benefits such as antimicrobial activity, immunological effects, and the ability to modulate the intestinal microbiota. However, just a small number of them are manufactured at an industrial scale and included in commercial products. The under exploitation of L. salivarius strains that remain in the freezer of companies is due to their incapacity to overcome the environmental stresses induced by production and stabilization processes.The present study summarizes the functionalities and applications of L. salivarius reported to date. It aims also at providing a critical evaluation of the literature available on the manufacturing steps of L. salivarius concentrates, the bacterial quality after each step of the process, and the putative degradation and preservation mechanisms. Here, we highlight the principal issues and future research challenges for improving the production and long-term preservation at the industrial scale of this microorganism, and probably of other probiotics.Key points• L. salivarius beneficial properties and commercialized products.• Production conditions and viability of L. salivarius after stabilization processes.• Prospects for identifying preservation mechanisms to improve L. salivarius stability.
Indexed as
Identifiers
34889985What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.