Evidence map›Paper›PMID 34889892›Full record

ReviewCurrent issues in molecular biology2021

A Critical Review: Recent Advancements in the Use of CRISPR/Cas9 Technology to Enhance Crops and Alleviate Global Food Crises.

Adnan Rasheed, Rafaqat Ali Gill, Muhammad Umair Hassan, Athar Mahmood, Sameer Qari, Qamar U Zaman, Muhammad Ilyas, Muhammad Aamer, Maria Batool, Huijie Li and 1 more

Abstract readReview
In one paragraph

Review in Current issues in molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Integrating physiological and multi-omics methods to elucidate heat stress tolerance for sustainable rice production.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024
    Review
  11. Article
  12. The Future of Food.Foods (Basel, Switzerland) · 2024
    Review
  13. Drought stress inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024
    Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adnan RasheedKey Laboratory of Crops Physiology, Ecology and Genetic Breeding, Ministry of Education/College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China.
Rafaqat Ali GillOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.ORCID 0000-0001-6553-9312
Muhammad Umair HassanResearch Center on Ecological Sciences, Jiangxi Agricultural University, Nanchang 330045, China.
Athar MahmoodDepartment of Agronomy, University of Agriculture, Faisalabad 38040, Pakistan.
Sameer QariBiology Department, (Genetics and Molecular Biology Central Laboratory), Aljumum University College, Umm Al-Qura University, Makkah 24382, Saudi Arabia.ORCID 0000-0001-9424-5217
Qamar U ZamanOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.ORCID 0000-0002-2665-7436
Muhammad IlyasUniversity College of Dera Murad Jamali, Nasirabad 80700, Balochistan, Pakistan.
Muhammad AamerResearch Center on Ecological Sciences, Jiangxi Agricultural University, Nanchang 330045, China.ORCID 0000-0003-1612-5126
Maria BatoolCollege of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Huijie LiKey Laboratory of Crops Physiology, Ecology and Genetic Breeding, Ministry of Education/College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China.
Ziming WuKey Laboratory of Crops Physiology, Ecology and Genetic Breeding, Ministry of Education/College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China.

Funding

National Natural Science Foundation of China 31560350、31760350 and 7196302
6 · The paper itself

Abstract

Genome editing (GE) has revolutionized the biological sciences by creating a novel approach for manipulating the genomes of living organisms. Many tools have been developed in recent years to enable the editing of complex genomes. Therefore, a reliable and rapid approach for increasing yield and tolerance to various environmental stresses is necessary to sustain agricultural crop production for global food security. This critical review elaborates the GE tools used for crop improvement. These tools include mega-nucleases (MNs), such as zinc-finger nucleases (ZFNs), and transcriptional activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeats (CRISPR). Specifically, this review addresses the latest advancements in the role of CRISPR/Cas9 for genome manipulation for major crop improvement, including yield and quality development of biotic stress- and abiotic stress-tolerant crops. Implementation of this technique will lead to the production of non-transgene crops with preferred characteristics that can result in enhanced yield capacity under various environmental stresses. The CRISPR/Cas9 technique can be combined with current and potential breeding methods (e.g., speed breeding and omics-assisted breeding) to enhance agricultural productivity to ensure food security. We have also discussed the challenges and limitations of CRISPR/Cas9. This information will be useful to plant breeders and researchers in the thorough investigation of the use of CRISPR/Cas9 to boost crops by targeting the gene of interest.

Indexed as

CRISPR-Cas SystemsGene EditingPlant BreedingCrops, AgriculturalDisease ResistanceFood QualityFood SupplyGenetic EngineeringGenome, PlantGenomicsPlants, Genetically Modifiedabiotic stressesbioticCRISPR/Cas9cropsyield

Identifiers

PMID34889892
PMCPMC8929161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.