Evidence map›Paper›PMID 34889698›Full record

ArticleBioengineered2021

Expression and role of microRNA-212/nuclear factor I-A in depressive mice.

Liang Si, Yanyan Wang, Min Liu, Lifeng Yang, Li Zhang

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The role of microRNAs in depression.Frontiers in pharmacology · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Liang SiDepartment of Psychiatry, Wuhan Mental Health Center, Wuhan, China.
Yanyan WangDepartment of Psychiatry, Wuhan Mental Health Center, Wuhan, China.
Min LiuDepartment of Psychiatry, Wuhan Mental Health Center, Wuhan, China.
Lifeng YangDepartment of Psychiatry, Wuhan Mental Health Center, Wuhan, China.
Li ZhangDepartment of Psychiatry, Affiliated Wuhan Mental Health Center, Tongji Medical College of Huazhong University of Science & Technology, Wuhan, China.
Huazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is characterized by persistent depressed mood and cognitive dysfunction, severely impacting human health. In the present study, we aimed to explore the role and mechanism of microRNA (miR)-212 in depression

Indexed as

Gene Expression RegulationAnimalsApoptosisBase SequenceBehavior, AnimalChronic DiseaseDepressionHippocampusInflammationMaleMiceMice, Inbred C57BLMicroRNAsNeuronsNFI Transcription FactorsProtective AgentsMicroRNAsMIRN212 microRNA, mouseNfia protein, mouseNFI Transcription FactorsProtective Agentschronic unpredictable mild stressdepressionhippocampusmiR-212NFIA

Identifiers

PMID34889698
PMCPMC8810195
OpenAlexW4200217145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.