ArticleJournal of clinical hypertension (Greenwich, Conn.)2022
Impact of blood pressure changes on myocardial work indices in hypertensive patients in a day.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Distinct Echocardiographic Phenotypes in Primary vs. Secondary Iron Overload Cardiomyopathy: A Pilot Study on Myocardial Work Indices.Medical sciences (Basel, Switzerland) · 2026Article
- A Pilot Human Study on Dual Photoplethysmography for Continuously Monitoring Pulse Wave Velocity and Blood Pressure.IEEE journal on flexible electronics · 2025Article
- Mitophagy mediated by HIF-1α/FUNDC1 signaling in tubular cells protects against renal ischemia/reperfusion injury.Renal failure · 2024Article
- Myocardial work alterations with progressive left ventricular hypertrophy in patients with hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Hypertensive Heart Disease: Mechanisms, Diagnosis and Treatment.Reviews in cardiovascular medicine · 2024Review
- Echocardiographic Myocardial Work: A Novel Method to Assess Left Ventricular Function in Patients with Coronary Artery Disease and Diabetes Mellitus.Medicina (Kaunas, Lithuania) · 2024Review
- Global and regional myocardial function assessment in symptomatic patients with chronic coronary syndrome using longitudinal strain and noninvasive myocardial work.The international journal of cardiovascular imaging · 2023Article
- Noninvasive assessment of myocardial work during left ventricular isovolumic relaxation in patients with diastolic dysfunction.BMC cardiovascular disorders · 2023Article
- The value of myocardial work in the estimation of left ventricular systolic function in patients with coronary microvascular disease: A study based on adenosine stress echocardiography.Frontiers in cardiovascular medicine · 2023Article
- Left Ventricular Diastolic Response to Isometric Handgrip Exercise in Physically Active and Sedentary Individuals.Journal of cardiovascular development and disease · 2022Article
- Impact of blood pressure changes on myocardial work indices in hypertensive patients in a day.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Do diurnal changes in blood pressure affect myocardial work indices?Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
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Authors and funding
7 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evaluating left ventricular function through instantaneous left ventricular deformation parameters might not always be accurate for patients with high fluctuations in blood pressure value due to afterload dependence. Myocardial work (MW) is a more advanced tool that combines global myocardial longitudinal strain (GLS) with LV (left ventricular) systolic pressure. The purpose of this study was to investigate the effect of blood pressure changes on MW indices in the population with normal blood pressure and hypertension in a day. A total of 117 participants (34 control subjects and 83 hypertensive patients) underwent echocardiographic measurements at rest, twice a day. Simultaneously, the brachial blood pressure was also measured. LV pressure-strain loop (PSL) was used to calculate global work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE). The differences in the GLS and MW indices between the groups were compared, and the correlation of blood pressure changes with the changes in GLS and MW indices were evaluated. Compared to the control group, the hypertensive group showed higher GWI, GCW, and GWW but lower GLS and GWE. Absolute changes in blood pressure, GLS, and MW indices in hypertensive patients were significantly higher than that of the control subjects. Blood pressure changes had significant univariate correlation with changes in GLS and MW indices. In conclusion, significant fluctuations in blood pressure could induce changes in MW indices to preserve left ventricular systolic function. Repeated assessment of MW indices is necessary for hypertensive patients with large blood pressure fluctuations.
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