ArticlePublic health nutrition2022
Association between iron supplementation and the presence of diarrhoea in Peruvian children aged 6-59 months: analysis of the database of the Demographic and Family Health Survey in Peru (DHS, Peru), years 2009-2019.
Article in Public health nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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3 authors at 2 institutions in 2 countries.
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Abstract
introductionAccording to the WHO, anaemia is a severe public health problem when the prevalence is ≥ 40 %. In 2019, in Peru, 40·1 % of children (aged 6 to 35 months) are diagnosed as anaemic. This is a concern since, despite the efforts of the governments to reduce the prevalence, the problem has stagnated since 2011. The treatment applied to deal with anaemia is Fe supplementation. Although Fe is essential for cell function, an excess can produce adverse responses, such as gut inflammation affecting microbiota and resulting in diarrhoeic episodes.
objectiveTo determine the association between diarrhoea and Fe supplementation in children with and without anaemia, controlling for different socio-demographic variables.
designWe conducted via logistic regression to obtain diarrhoea prevalence ratios (PR), adjusted by age, sex, geographic region, water and sanitation service, and rurality. The survey asked for recent episodes of diarrhoea during the last 7 d; similarly, after the consumption of Fe supplements during the last 12 months before the survey.
settingPeru.
participantsThe Demographic and Family Health Survey (DHS) is conducted annually at home among 14 202 children on average (2009-2019).
resultsFe supplementation in the last 7 d (PR = 1·09) or the last 12 months (PR = 1·19) (
conclusionsFe supplementation is associated with diarrhoea and overuse in children should be avoided.
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