Evidence map›Paper›PMID 34889108›Full record

ArticleJournal of the American Heart Association2021

Cryoballoon Ablation for the Treatment of Atrial Fibrillation in Patients With Concomitant Heart Failure and Either Reduced or Preserved Left Ventricular Ejection Fraction: Results From the Cryo AF Global Registry.

Roberto Rordorf, Fernando Scazzuso, Kyoung Ryul Julian Chun, Surinder Kaur Khelae, Fred J Kueffer, Kendra M Braegelmann, Ken Okumura, Fawzia Al-Kandari, Young Keun On, Csaba Földesi and 1 more

Erratum issuedOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
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  4. Safety, efficacy, and quality of life outcomes of pulsed field ablation in Japanese patients with atrial fibrillation: results from the PULSED AF trial.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  5. Article
  6. Review
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  8. 2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  9. Article
  10. Role of CHAJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Article
  11. Observational
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 9 countries.

Roberto RordorfArrhythmias Unit Fondazione IRCCS Policlinico S. Matteo Pavia Italy.ORCID 0000-0003-4111-1690
Fernando ScazzusoInstitituo Cardiovascular Buenos Aires Buenos Aires Argentina.ORCID 0000-0002-1623-0535
Kyoung Ryul Julian ChunCardioangiologisches Centrum Bethanien Frankfurt Germany.ORCID 0000-0002-2355-6015
Surinder Kaur KhelaeInstitut Jantung Negara - National Heart Institute Kuala Lumpur Malaysia.
Fred J KuefferMedtronic, Inc. Minneapolis MN.
Kendra M BraegelmannMedtronic, Inc. Minneapolis MN.
Ken OkumuraSaiseikai Kumamoto Hospital Kumamoto Japan.
Fawzia Al-KandariChest Disease Hospital Kuwait City Kuwait.
Young Keun OnDivision of Cardiology Department of Internal Medicine Heart Vascular and Stroke InstituteSamsung Medical CenterSungkyunkwan University School of Medicine Seoul Republic of Korea.
Csaba FöldesiGottsegen György Országos Kardiológiai Intézet Budapest Hungary.ORCID 0000-0002-5033-117X
Cryo AF Global Registry Investigators
Medtronic (United States) · USCardiovascular Center Bethanien · DEChest Diseases Hospital · KWGottsegen National Cardiovascular Center · HUInstituto Cardiovascular de Buenos Aires · ARNational Heart Institute · MYPoliclinico San Matteo Fondazione · ITSaiseikai Kumamoto Hospital · JPSamsung Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Heart failure (HF) and atrial fibrillation (AF) often coexist; yet, outcomes of ablation in patients with AF and concomitant HF are limited. This analysis assessed outcomes of cryoablation in patients with AF and HF. Methods and Results The Cryo AF Global Registry is a prospective, multicenter registry of patients with AF who were treated with cryoballoon ablation according to routine practice at 56 sites in 26 countries. Patients with baseline New York Heart Association class I to III (HF cohort) were compared with patients without HF. Freedom from atrial arrhythmia recurrence ≥30 seconds, safety, and health care utilization over 12-month follow-up were analyzed. A total of 1303 patients (318 HF) were included. Patients with HF commonly had preserved left ventricular ejection fraction (81.6%), were more often women (45.6% versus 33.6%) with persistent AF (25.8% versus 14.3%), and had a larger left atrial diameter (4.4±0.9 versus 4.0±0.7 cm). Serious procedure-related complications occurred in 4.1% of patients with HF and 2.6% of patients without HF (

Indexed as

Atrial FibrillationCatheter AblationCryosurgeryHeart FailureFemaleHumansMaleProspective StudiesRegistriesStroke VolumeTreatment OutcomeVentricular Function, Leftatrial fibrillationcatheter ablationheart failure

Identifiers

PMID34889108
PMCPMC9075259
OpenAlexW4200286361

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.