Evidence map›Paper›PMID 34888744›Full record

ReviewJournal of neurovirology2022

Clinical profile of children with parechovirus meningitis in Singapore.

Jessica Hui Yin Tan, Chew Thye Choong, Nancy Wen Sim Tee, Chia Yin Chong, Koh Cheng Thoon, Matthias Maiwald, Elis Yue Xian Lee, Melody Si Shan Tan, Natalie Woon Hui Tan

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neurovirology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jessica Hui Yin TanDepartment of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore. Jessica.Tan.hy@singhealth.com.sg.
Chew Thye ChoongDepartment of Paediatrics, Neurology Service, KK Women's and Children's Hospital, Singapore, Singapore.
Nancy Wen Sim TeeDepartment of Laboratory Medicine, National University Hospital, Singapore, Singapore.
Chia Yin ChongDepartment of Paediatrics, Infectious Disease Service, KK Women's and Children's Hospital, Singapore, Singapore.
Koh Cheng ThoonDepartment of Paediatrics, Infectious Disease Service, KK Women's and Children's Hospital, Singapore, Singapore.
Matthias MaiwaldDepartment of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, Singapore, Singapore.
Elis Yue Xian LeeDepartment of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore.
Melody Si Shan TanYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Natalie Woon Hui TanDepartment of Paediatrics, Infectious Disease Service, KK Women's and Children's Hospital, Singapore, Singapore.
KK Women's and Children's Hospital · SGNanyang Technological University · SGNational University Hospital · SGNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human parechovirus (HPeV) is one of the most common causes of aseptic meningitis in children worldwide. This study aims to review the epidemiology, clinical presentation, and cerebrospinal fluid (CSF) findings in HPeV meningitis and compare these with Enterovirus (EV) meningitis. This is a retrospective study of children aged ≤ 1 year admitted for HPeV meningitis between November 2015 and July 2017, with positive CSF HPeV PCR and negative blood and CSF bacterial cultures. The clinical findings were compared with a historical cohort of children with EV meningitis admitted between July 2008 and July 2011. There were 71 children with HPeV meningitis, aged between 2 and 127 days, with the majority (96%) being ≤ 90 days old. The most common symptoms reported were poor feeding (42%), tachycardia out of proportion to fever (27%), and lethargy (20%). Only 2 patients (3%) had CSF pleocytosis. Cerebral spinal fluid white blood cell counts ranged from 0 to 28 cells/mm

Indexed as

EnterovirusEnterovirus InfectionsMeningitis, ViralParechovirusPicornaviridae InfectionsAdolescentAdultAgedAged, 80 and overChildChild, PreschoolHumansInfantLeukocytosisMiddle AgedPrevalenceEnterovirusMeningitisParechovirusPediatricsPleocytosisPolymerase chain reaction (PCR)

Identifiers

PMID34888744
OpenAlexW4200300025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.