ArticleInteractive cardiovascular and thoracic surgery2022
Results from a multicentre evaluation of plug use for left ventricular assist device explantation.
Article in Interactive cardiovascular and thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Surgical Approaches to Left Ventricular Assist Device Deactivation: Lessons From Remission From Stage D Heart Failure.Annals of thoracic surgery short reports · 2026Article
- Decommissioning of Durable Left Ventricular Assist Devices.CJC open · 2026Article
- A study on the global patterns in the design and development of ventricular assist devices: a visualization approach.Frontiers in cardiovascular medicine · 2025Article
- Deactivation of LVAD support for myocardial recovery-surgical perspectives.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024Review
- Predictors of long-term success after successful explantation of continuous flow left ventricular assist device support.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Patient-tailored silicone plug for HeartMate 3™ left ventricular assist device explantation.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2024Article
- Left ventricular assist device explantation using a new double-patch technique†.Interdisciplinary cardiovascular and thoracic surgery · 2023Article
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Authors and funding
18 authors at 11 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesMyocardial recovery allows for left ventricular assist device (LVAD) explantations after long-term support. Several surgical approaches, including interventional decommissioning, off-pump explantation using a custom-made plug and complete LVAD removal through redo sternotomy, have been described. We present the results from an evaluation of the long-term follow-up of patients who received a titanium sintered plug after LVAD explantation.
methodsWe performed a retrospective, European, multicentre analysis of patients who received a titanium sintered plug to seal the apical fixation ring after LVAD explantation. Data were collected from a questionnaire that included demographics, procedural details and follow-up information.
resultsOut of 54 contacted centres in 12 countries (n = 179 patients), a total of 68 patients were successfully included in the study. The median follow-up was 34 months (interquartile range: 17-58.5 months); 57 (84%) patients had >1-year follow-up. At the time of the last follow-up, 55 (81%) patients were alive, with a Kaplan-Meier 1-year survival of 90.1% (95% confidence interval: 84.0-98.1%) and a 5-year survival of 80.0% (95% confidence interval: 68.4-92.9%). One patient (1.5%) developed a plug infection originating from an infected part of the incorporated driveline and, after complete removal, is currently in good condition. No postoperative stroke has been reported after plug implantation.
conclusionsIn this European multicentre study, the use of a custom-made titanium plug to close the apical fixation ring after LVAD explantation resulted in a low incidence of plug-related complications. With the volume of patients undergoing LVAD explantations after myocardial recovery increasing, the plug has evolved as a simple alternative to more invasive device explantation procedures or decommissioning with a high risk for infection of the remaining system or stroke.
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