Evidence map›Paper›PMID 34888570›Full record

ArticleCircular economy and sustainability2021

Vaccine Innovation for Pandemic Preparedness: Patent Landscape, Global Sustainability, and Circular Bioeconomy in Post-COVID-19 era.

Cristina Possas, Adelaide Maria de Souza Antunes, Alessandra Moreira de Oliveira, Cristina d'Urso de Souza Mendes Santos, Mateus Pinheiro Ramos, Suzanne de Oliveira Rodrigues Schumacher, Akira Homma

Open access · greenAbstract read
In one paragraph

Article in Circular economy and sustainability, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Cristina PossasBio-Manguinhos, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.ORCID 0000-0002-2886-2812
Adelaide Maria de Souza AntunesSchool of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0002-2245-7517
Alessandra Moreira de OliveiraSchool of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0003-4203-6637
Cristina d'Urso de Souza Mendes SantosNational Institute of Industrial Property, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0002-5019-0645
Mateus Pinheiro RamosSchool of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0001-5318-020X
Suzanne de Oliveira Rodrigues SchumacherSchool of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0001-8210-5663
Akira HommaBio-Manguinhos, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0002-4641-8491
Universidade Federal do Rio de Janeiro · BRFundação Oswaldo Cruz · BRInstituto Nacional da Propriedade Industrial · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this article, we present breakthroughs and challenges in vaccine development for COVID-19 pandemic, discussing issues related to pandemic preparedness and their implications for circular bioeconomy and sustainability. Notwithstanding the unprecedented accelerated speed of COVID-19 vaccine development, just 9 months after the emergence of the pandemic in Wuhan, China, benefiting from previous developments in SARS and MERS vaccines, significant gaps persist in global vaccine preparedness. These gaps include issues related to immunity and protection, particularly to the limited vaccine protection against recent emergence of concerning new viral variants in the UK, South Africa, and Brazil and the consequent need for vaccine redesign. We examine these gaps and discuss the main issues that could impact on global vaccine availability in the current pandemic scenario: (1) breakthroughs and constraints in development and production of leading global COVID-19 vaccines; (2) innovation and technological development advances and gaps, providing information on global patent assignees for COVID-19, SARS, and MERS vaccine patents; (3) local capacity for development and production of COVID-19, SARS, and MERS vaccines in three emerging agro-based countries (India, Brazil, and South Africa); and (4) future scenarios, examining how these issues and vaccines redesign for new SARS-CoV-2 variants could impact on global access to vaccines and implications for circular bioeconomy and sustainability in the post-COVID era.

Indexed as

Circular economyCOVID-19MERSPandemic preparednessSARSVaccine innovation

Identifiers

PMID34888570
PMCPMC8280571
OpenAlexW3186957333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.