Evidence map›Paper›PMID 34888530›Full record

ArticleCurrent research in toxicology2021

The new psychoactive substances 25H-NBOMe and 25H-NBOH induce abnormal development in the zebrafish embryo and interact in the DNA major groove.

Wellington Alves de Barros, Camila da Silva Nunes, Juliana Alves da Costa Ribeiro Souza, Igor José Dos Santos Nascimento, Isis Martins Figueiredo, Thiago Mendonça de Aquino, Leonardo Vieira, Davi Farias, Josué Carinhanha Caldas Santos, Ângelo de Fátima

Open access · goldAbstract read
In one paragraph

Article in Current research in toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Sublethal Concentrations of 2C-I and 25I-NBOMe Designer Drugs ImpactInternational journal of molecular sciences · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Wellington Alves de BarrosDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Camila da Silva NunesInstituto de Química e Biotecnologia, Universidade Federal de Alagoas, Maceió, AL, Brazil.
Juliana Alves da Costa Ribeiro SouzaDepartamento de Biologia Molecular, Universidade Federal da Paraíba, João Pessoa, PB, Brazil.
Igor José Dos Santos NascimentoInstituto de Química e Biotecnologia, Universidade Federal de Alagoas, Maceió, AL, Brazil.
Isis Martins FigueiredoInstituto de Química e Biotecnologia, Universidade Federal de Alagoas, Maceió, AL, Brazil.
Thiago Mendonça de AquinoInstituto de Química e Biotecnologia, Universidade Federal de Alagoas, Maceió, AL, Brazil.
Leonardo VieiraDepartamento de Biologia Molecular, Universidade Federal da Paraíba, João Pessoa, PB, Brazil.
Davi FariasDepartamento de Biologia Molecular, Universidade Federal da Paraíba, João Pessoa, PB, Brazil.
Josué Carinhanha Caldas SantosInstituto de Química e Biotecnologia, Universidade Federal de Alagoas, Maceió, AL, Brazil.
Ângelo de FátimaDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Universidade Federal de Alagoas · BRUniversidade Federal da Paraíba · BRUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxicological effects of 25H-NBOMe and 25H-NBOH recreational drugs on zebrafish embryos and larvae at the end of 96 h exposure period were demonstrated. 25H-NBOH and 25H-NBOMe caused high embryo mortality at 80 and 100 µg mL

Indexed as

DNA interactionEmbryo mortalityMalformationPhenethylaminesRecreational drugs

Identifiers

PMID34888530
PMCPMC8637007
OpenAlexW3215150116

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.