Evidence map›Paper›PMID 34888194›Full record

ReviewQuantitative imaging in medicine and surgery2021

Deep learning for automatic target volume segmentation in radiation therapy: a review.

Hui Lin, Haonan Xiao, Lei Dong, Kevin Boon-Keng Teo, Wei Zou, Jing Cai, Taoran Li

Open access · diamondAbstract readReview
In one paragraph

Review in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Hui LinDepartment of Radaition Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Haonan XiaoDepartment of Health Technology & Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Lei DongDepartment of Radaition Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Kevin Boon-Keng TeoDepartment of Radaition Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Wei ZouDepartment of Radaition Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jing CaiDepartment of Health Technology & Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Taoran LiDepartment of Radaition Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
University of Pennsylvania · USHong Kong Polytechnic University · HKUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep learning, a new branch of machine learning algorithm, has emerged as a fast growing trend in medical imaging and become the state-of-the-art method in various clinical applications such as Radiology, Histo-pathology and Radiation Oncology. Specifically in radiation oncology, deep learning has shown its power in performing automatic segmentation tasks in radiation therapy for Organs-At-Risks (OAR), given its potential in improving the efficiency of OAR contouring and reducing the inter- and intra-observer variabilities. The similar interests were shared for target volume segmentation, an essential step of radiation therapy treatment planning, where the gross tumor volume is defined and microscopic spread is encompassed. The deep learning-based automatic segmentation method has recently been expanded into target volume automatic segmentation. In this paper, the authors summarized the major deep learning architectures of supervised learning fashion related to target volume segmentation, reviewed the mechanism of each infrastructure, surveyed the use of these models in various imaging domains (including Computational Tomography with and without contrast, Magnetic Resonant Imaging and Positron Emission Tomography) and multiple clinical sites, and compared the performance of different models using standard geometric evaluation metrics. The paper concluded with a discussion of open challenges and potential paths of future research in target volume automatic segmentation and how it may benefit the clinical practice.

Indexed as

auto segmentationDeep learningradiation therapytarget volume delineation

Identifiers

PMID34888194
PMCPMC8611469
OpenAlexW3206966550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.