Evidence map›Paper›PMID 34887997›Full record

ArticleOxidative medicine and cellular longevity2021

A Protein from

Shiting Yu, Bing Han, Xin Xing, Yixuan Li, Daqing Zhao, Meichen Liu, Siming Wang

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. CanInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Network pharmacology prediction to discover the potential pharmacological action mechanism of Rhizoma Dioscoreae for liver regeneration.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024
    Article
  5. Article
  6. Aflatoxin BToxins · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shiting YuJilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China.ORCID https://orcid.org/0000-0002-8784-7743
Bing HanJilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China.ORCID https://orcid.org/0000-0003-2247-375X
Xin XingJilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China.ORCID https://orcid.org/0000-0002-1854-7499
Yixuan LiJilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China.ORCID https://orcid.org/0000-0002-5997-6433
Daqing ZhaoJilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China.ORCID https://orcid.org/0000-0001-5678-7410
Meichen LiuJilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China.ORCID https://orcid.org/0000-0002-3657-0748
Siming WangJilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China.ORCID https://orcid.org/0000-0001-9299-8477
Changchun University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leydig cell injury has been described as a primary driver of testicular dysfunction and is affected by oxidative stress.

Indexed as

AnimalsApoptosisbcl-2-Associated X ProteinDioscoreaHydrocortisoneLeydig CellsMaleNF-E2-Related Factor 2Oxidative StressPlant ProteinsProto-Oncogene Proteins c-bcl-2RatsRats, Sprague-DawleyRNA InterferenceRNA, Small InterferingSmad2 Proteinbcl-2-Associated X ProteinHydrocortisoneNF-E2-Related Factor 2Plant ProteinsProto-Oncogene Proteins c-bcl-2RNA, Small InterferingSmad2 ProteinSmad3 ProteinTransforming Growth Factor beta1

Identifiers

PMID34887997
PMCPMC8651383
OpenAlexW3215531065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.