Evidence map›Paper›PMID 34887958›Full record

ArticleJournal of arrhythmia2021

Evaluation of potential underuse of cardiac resynchronization therapy for heart failure with reduced ejection fraction.

Makoto Takano, Yui Nakayama, Hisao Matsuda, Tomoo Harada, Yoshihiro J Akashi

Open access · goldAbstract read
In one paragraph

Article in Journal of arrhythmia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Makoto TakanoDivision of Cardiology Department of Internal Medicine Yokohama City Seibu Hospital St. Marianna University School of Medicine Yokohama Yokohama City Japan.ORCID https://orcid.org/0000-0002-1198-1049
Yui NakayamaDivision of Cardiology Department of Internal Medicine Yokohama City Seibu Hospital St. Marianna University School of Medicine Yokohama Yokohama City Japan.
Hisao MatsudaDivision of Cardiology Department of Internal Medicine Yokohama City Seibu Hospital St. Marianna University School of Medicine Yokohama Yokohama City Japan.
Tomoo HaradaDivision of Cardiology Department of Internal Medicine St. Marianna University School of Medicine Kawasaki Japan.
Yoshihiro J AkashiDivision of Cardiology Department of Internal Medicine St. Marianna University School of Medicine Kawasaki Japan.
St. Marianna University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe number of patients with chronic heart failure is increasing in Japan. However, the annual number of patients with heart failure who receive cardiac resynchronization therapy (CRT) has been constant in the last few years. In this study, we evaluated patients who did not receive CRT despite being eligible for this treatment to elucidate the clinical impact of CRT administration.

methodsWe assessed 214 patients with a left ventricular ejection fraction (LVEF) ≤ 50% (excluding patients treated with CRT) who underwent transthoracic echocardiography between January and May 2020 at our institution. The patients were stratified into two groups: Group A (n = 26; patients eligible for CRT) and Group B (n = 188; patients ineligible for CRT); however, all patients only received pharmacological therapy. We retrospectively analyzed the prognosis of these patients with respect to the cumulative number of hospitalizations for heart failure and cardiogenic deaths.

resultsWe observed no significant between-group differences in age, sex, and severity/diagnosis of organic heart disease. Group A had a significantly higher number of hospitalizations for heart failure and cardiogenic deaths than Group B (log-rank test,

conclusionsThis study shows that 12% of patients were eligible for CRT. However, the implantation rate was low and no one was implanted. CRT is underutilized in patients who have heart failure with reduced LVEF. Therefore, we strongly recommend CRT for patients with indications for CRT.

Indexed as

cardiac resynchronization therapyguidelineheart failureimplantable cardioverter defibrillatorleft bundle branch block

Identifiers

PMID34887958
PMCPMC8637101
OpenAlexW3205700309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.