Evidence map›Paper›PMID 34887945›Full record

ArticleJournal of arrhythmia2021

2021 Focused update of the 2017 consensus guidelines of the Asia Pacific Heart Rhythm Society (APHRS) on stroke prevention in atrial fibrillation.

Tze-Fan Chao, Boyoung Joung, Yoshihide Takahashi, Toon Wei Lim, Eue-Keun Choi, Yi-Hsin Chan, Yutao Guo, Charn Sriratanasathavorn, Seil Oh, Ken Okumura and 1 more

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Comparisons of effectiveness and safety between on-label dosing, off-label underdosing, and off-label overdosing in Asian and non-Asian atrial fibrillation patients treated with rivaroxaban: a systematic review and meta-analysis of observational studies.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Pooled it
  3. Pooled it
  4. Guideline
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  6. Standard-Intensity Versus Low-Intensity Anticoagulation with Warfarin in Asian Patients with Atrial Fibrillation: A Multi-Center, Randomized Controlled Trial.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Trial
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  13. Review
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  16. Performance of DOAC and HAS-BLED scores in predicting major bleeding in Asian patients with non-valvular atrial fibrillation receiving direct oral anticoagulants.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  17. Direct oral anticoagulants in very elderly and high-bleeding-risk patients with atrial fibrillation often excluded from oral anticoagulation therapy: a nationwide population-based cohort study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  18. Timing of stroke risk reassessment in atrial fibrillation patients with a CHA2DS2-VA score of 0 or 1: the Norwegian AFNOR study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  19. 2025 Thai guideline for the diagnosis and management of atrial fibrillation.Asian biomedicine : research, reviews and news · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tze-Fan ChaoDivision of Cardiology Department of Medicine Taipei Veterans General Hospital Taipei Taiwan.ORCID https://orcid.org/0000-0002-6587-3094
Boyoung JoungDivision of Cardiology Department of Internal Medicine Yonsei University College of Medicine Seoul Republic of Korea.ORCID https://orcid.org/0000-0001-9036-7225
Yoshihide TakahashiThe Department of Advanced Arrhythmia Research Tokyo Medical and Dental University Tokyo Japan.
Toon Wei LimNational University Heart Centre National University Hospital Singapore Singapore.
Eue-Keun ChoiDepartment of Internal Medicine Seoul National University Hospital Seoul Republic of Korea.ORCID https://orcid.org/0000-0002-0411-6372
Yi-Hsin ChanMicroscopy Core Laboratory Chang Gung Memorial Hospital Linkou Taoyuan Taiwan.
Yutao GuoPulmonary Vessel and Thrombotic Disease Chinese PLA General Hospital Beijing China.ORCID https://orcid.org/0000-0002-7626-7751
Charn SriratanasathavornHer Majesty Cardiac Center Siriraj Thailand.
Seil OhDepartment of Internal Medicine Seoul National University Hospital Seoul Republic of Korea.
Ken OkumuraDivision of Cardiology Saiseikai Kumamoto Hospital Kumamoto Japan.
Gregory Y H LipLiverpool Centre for Cardiovascular Science University of Liverpool & Liverpool Heart and Chest Hospital Liverpool UK.ORCID https://orcid.org/0000-0002-7566-1626

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The consensus of the Asia Pacific Heart Rhythm Society (APHRS) on stroke prevention in atrial fibrillation (AF) has been published in 2017 which provided useful clinical guidance for cardiologists, neurologists, geriatricians, and general practitioners in Asia-Pacific region. In these years, many important new data regarding stroke prevention in AF were reported. The Practice Guidelines subcommittee members comprehensively reviewed updated information on stroke prevention in AF, and summarized them in this 2021 focused update of the 2017 consensus guidelines of the APHRS on stroke prevention in AF. We highlighted and focused on several issues, including the importance of AF Better Care (ABC) pathway, the advantages of non-vitamin K antagonist oral anticoagulants (NOACs) for Asians, the considerations of use of NOACs for Asian patients with AF with single 1 stroke risk factor beyond gender, the role of lifestyle factors on stroke risk, the use of oral anticoagulants during the "coronavirus disease 2019" (COVID-19) pandemic, etc. We fully realize that there are gaps, unaddressed questions, and many areas of uncertainty and debate in the current knowledge of AF, and the physician's decision remains the most important factor in the management of AF.

Indexed as

APHRSatrial fibrillationconsensus guidelinesstroke prevention

Identifiers

PMID34887945
PMCPMC8637102

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.