Evidence map›Paper›PMID 34887849›Full record

ArticleFrontiers in immunology2021

High Dimensional Immune Profiling Reveals Different Response Patterns in Active and Latent Tuberculosis Following Stimulation With Mycobacterial Glycolipids.

Carolina S Silva, Christopher Sundling, Elin Folkesson, Gabrielle Fröberg, Claudia Nobrega, João Canto-Gomes, Benedict J Chambers, Tadepally Lakshmikanth, Petter Brodin, Judith Bruchfeld and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Carolina S SilvaLife and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal.
Christopher SundlingDivision of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
Elin FolkessonDivision of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
Gabrielle FröbergDivision of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
Claudia NobregaLife and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal.
João Canto-GomesLife and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal.
Benedict J ChambersCenter for Infectious Medicine, Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden.
Tadepally LakshmikanthScience for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Petter BrodinScience for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Judith BruchfeldDivision of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
Jérôme NigouInstitut de Pharmacologie et de Biologie Structurale, Université de Toulouse, Centre National de la Recherche Scientifique (CNRS), Université Paul Sabatier, Toulouse, France.
Margarida Correia-NevesLife and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal.
Gunilla KälleniusDivision of Infectious Diseases, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
Karolinska Institutet · SEUniversity of Minho · PTScience for Life Laboratory · SECentre National de la Recherche Scientifique · FRKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upon infection with

Indexed as

AdultAgedAged, 80 and overAntigens, BacterialB-LymphocytesCase-Control StudiesCohort StudiesCytokinesFemaleGlycolipidsHumansIn Vitro TechniquesKiller Cells, NaturalLatent TuberculosisMaleMiddle AgedAntigens, BacterialCytokinesGlycolipidsphosphatidylinositol mannosidePhosphatidylinositolsTLR2 protein, humanToll-Like Receptor 2Tuberculinactive tuberculosis (ATB)hyporesponsivenesslatent tuberculosis (LTB)lipoarabinomannan (LAM)mycobacterial glycolipidsphosphatidylinositol mannoside (PIM)tuberculosis

Identifiers

PMID34887849
PMCPMC8650708
OpenAlexW3214796766

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.