Evidence map›Paper›PMID 34887841›Full record

ArticleFrontiers in microbiology2021

Overlapping Roles of Yeast Transporters Aqr1, Qdr2, and Qdr3 in Amino Acid Excretion and Cross-Feeding of Lactic Acid Bacteria.

George C Kapetanakis, Christos Gournas, Martine Prévost, Isabelle Georis, Bruno André

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Engineering small peptide secretion inFrontiers in bioengineering and biotechnology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

George C KapetanakisMolecular Physiology of the Cell, Université Libre de Bruxelles, Biopark, Gosselies, Belgium.
Christos GournasMicrobial Molecular Genetics Laboratory, Institute of Biosciences and Applications, National Centre for Scientific Research "Demokritos", Agia Paraskevi, Greece.
Martine PrévostStructure et Fonction des Membranes Biologiques, Université Libre de Bruxelles, Brussels, Belgium.
Isabelle GeorisTransport of Amino Acids, Sensing and Signaling in Eukaryotes, Labiris, Brussels, Belgium.
Bruno AndréMolecular Physiology of the Cell, Université Libre de Bruxelles, Biopark, Gosselies, Belgium.
Université Libre de Bruxelles · BENational Centre of Scientific Research "Demokritos" · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial species occupying the same ecological niche or codeveloping during a fermentation process can exchange metabolites and mutualistically influence each other's metabolic states. For instance, yeast can excrete amino acids, thereby cross-feeding lactic acid bacteria unable to grow without an external amino acid supply. The yeast membrane transporters involved in amino acid excretion remain poorly known. Using a yeast mutant overproducing and excreting threonine (Thr) and its precursor homoserine (Hom), we show that excretion of both amino acids involves the Aqr1, Qdr2, and Qdr3 proteins of the Drug H

Indexed as

amino acid excretionamino acid transportcross-feedingdrug H+ antiporterlactic acid bacteriaLactobacillus fermentumSaccharomyces cerevisiaeyeast

Identifiers

PMID34887841
PMCPMC8649695
OpenAlexW3215261941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.