ArticleInternational journal of general medicine2021
Frequencies of MNS Blood Group Antigens and Phenotypes in Southwestern Saudi Arabia.
Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 14 citations in OpenAlex.
- Hemolytic Transfusion Reaction due to Anti Jk Antibody, a Frequently Transient and Low-Titer Antibody Probably Not Detected in Pretransfusion Testing; A Case Report.Clinical case reports · 2025Article
- The MNS blood group system in Tunisian blood donors: common and rare alleles.Molecular biology reports · 2025Article
- Distribution and Genetic Characterization of the MNS Blood Group in Multi-Ethnic Populations of East China.Journal of blood medicine · 2025Article
- The Distributions of Duffy Antigens and Phenotypes Among Blood Donors in King Abdulaziz Medical City-Western Region, Saudi Arabia: A Cross-Sectional Study.International journal of general medicine · 2025Article
- Association of ABO blood group, Rh phenotype and MN blood group with susceptibility to COVID-19.PloS one · 2024Article
- The Incidences of KEL Blood Group Antigens and Phenotypes in Southwestern Saudi Arabia.International journal of general medicine · 2024Article
- Investigation of Wright Blood Group Alleles and Genotypes in Malaria-Endemic Area in Southwestern Saudi Arabia.International journal of general medicine · 2024Article
- Red Blood Cell Alloimmunization and Autoimmunization in Blood Transfusion-Dependent Sickle Cell Disease andAnemia · 2023Article
- Article
- Red Cell Alloimmunization and Autoimmunization Among Sickle Cell Disease and Thalassemia Patients in Jazan Province, Saudi Arabia.International journal of general medicine · 2022Article
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8 authors at 4 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeKnowledge of the prevalence of blood group antigens in a given population is important for the prevention of hemolytic reactions. The MNS blood group system (002) has four polymorphic antigens-M, N, S, and s. Anti-S and anti-s antibodies may result in immediate and delayed hemolytic transfusion reactions, and hemolytic disease of the fetus and newborn may occur. The present study investigated the frequencies of the main antigens and phenotypes of the MNS blood group system. SUBJECTS AND
methodsWe randomly obtained 149 samples from anonymous Saudi blood donors living in Jazan Province. Serotyping was conducted using a gel card to investigate (M, N, S, and s) antigens and phenotypes.
resultsThe frequencies of MNS antigens were as follows: M = 89.26%, N = 51.67%, S = 61.07%, and s = 82.55%. Regarding the MNS phenotypes, nine phenotypes were observed in the study population. The most common phenotype was M+N-S+s+ (n = 36, 24.16%), in contrast to the least common phenotype M+N-S-s- (n = 1, 0.67%). The prevalence of the MNS phenotypes in the current study population was highly and significantly different from that in Europeans (
conclusionIn summary, this study reports the frequencies of the MNS antigens and phenotypes in Jazan Province, Saudi Arabia. The most common phenotype was M+N-S+s+, whereas the least observed phenotype was M+N-S-s-. The outcomes of this study may assist the blood banks in Jazan Province to establish an extended phenotyping protocol including the MNS antigens, in particular S and s antigens, to preclude any alloimmunization events.
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