ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2021
Remnant Cholesterol is an Independent Predictor of New-Onset Diabetes: A Single-Center Cohort Study.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Association between remnant cholesterol and chronic kidney disease: Systematic review and meta-analysis.Diabetes, obesity & metabolism · 2025Pooled it
- Association of pre-pregnancy body mass index and first-trimester remnant cholesterol level with risk of large for gestational age.Journal of global health · 2026Article
- Discordance between remnant cholesterol and low-density lipoprotein cholesterol predicts incident hypertension: a 9-year prospective cohort study in Chinese adults.BMC cardiovascular disorders · 2026Article
- The mediating role of remnant cholesterol in the association between obstructive sleep apnea and diabetes: insights from two independent datasets.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Exploring the relationship between remnant cholesterol and diabetic kidney disease in Chinese type 2 diabetes patients.Frontiers in nutrition · 2026Article
- Association between Remnant Cholesterol and Metabolic Syndrome beyond Conventional Lipid Parameters in Middle Age and Elderly Population: Bushehr Elderly Health (BEH) cohort.Journal of diabetes and metabolic disorders · 2025Article
- A cross-sectional analysis of remnant cholesterol-diabetes association in US adults.Scientific reports · 2025Article
- Remnant cholesterol predicts the development of type 2 diabetes in patients with nonalcoholic fatty liver disease.Diabetology & metabolic syndrome · 2025Article
- The mediating role of inflammation-related indicators in the association of remnant cholesterol with gestational diabetes mellitus.Journal of global health · 2025Article
- Association of remnant cholesterol with depression, type 2 diabetes, and their coexistence.BMC psychiatry · 2025Article
- Association of baseline remnant cholesterol independent of LDL-cholesterol with newly diagnosed diabetes in the Chinese population.Biomolecules & biomedicine · 2025Article
- Association between non-high-density lipoprotein cholesterol-to-high-density lipoprotein cholesterol ratio and the risk of gestational diabetes: a retrospective study.Frontiers in nutrition · 2025Article
- Impact of remnant cholesterol on short-term mortality in acute decompensated heart failure: cohort study evidence from Jiangxi, China.Frontiers in endocrinology · 2025Article
- Diagnostic efficacy of remnant cholesterol inflammatory index in diabetic kidney disease: machine learning approaches.Frontiers in nutrition · 2025Article
- Association of Conventional and Unconventional Lipid Profiles with Visceral Fat Area in Overweight/Obese Individuals with Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Association of remnant cholesterol with insulin resistance and type 2 diabetes: mediation analyses from NHANES 1999-2020.Lipids in health and disease · 2024Observational
- Article
- Temporal changes in lipid concentrations and the prevalence of dyslipidemia among individuals with diabetes, prediabetes, and normal blood glucose from 2011 to 2015.Lipids in health and disease · 2024Article
- Association between Remnant Cholesterol and Metabolic Syndrome among Chinese Adults: Chinese Nutrition and Health Surveillance (2015-2017).Nutrients · 2024Article
- Nonlinear association between remnant cholesterol and reversion from impaired fasting glucose to normoglycemia: a multicenter cohort study.Lipids in health and disease · 2024Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeRemnant cholesterol (RC) is the cholesterol of triglyceride-rich lipoproteins, which has a high degree of atherogenic effect. To date, epidemiological evidence supports that higher RC levels lead to a greater risk of adverse cardiovascular events in patients with diabetes, but the nature of the association between RC levels and diabetes risk remains unclear. This study was designed to assess the association of RC with the risk of new-onset diabetes and to investigate whether there is a causal relationship between the two. PATIENTS AND
methodsThe subjects included 15,464 individuals of the general population who participated in a health examination. Subjects were quartered according to the RC quartile, and the Cox proportional hazard model was used to assess the independent association between RC and new-onset diabetes.
resultsDuring an average observation period of 6.13 years, 2.41% of the subjects were diagnosed with new-onset diabetes. Kaplan-Meier analysis showed that the 13-year cumulative diabetes rates corresponding to the RC quartile were 8.62%, 2.49%, 12.78%, and 17.91%. Multivariate Cox regression analysis indicated that higher RC levels were independently associated with an increased risk of new-onset diabetes (HR: 2.44, 95% CI: 1.50-3.89). Additionally, according to the results of receiver operating characteristic curve analysis, RC had the largest area under the curve (0.7314) compared to traditional lipid parameters in predicting new-onset diabetes.
conclusionThese results indicated that RC is an important independent predictor of new-onset diabetes in the general population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.