Evidence map›Paper›PMID 34887560›Full record

ArticleNature structural & molecular biology2021

Evolution of a histone variant involved in compartmental regulation of NAD metabolism.

Iva Guberovic, Sarah Hurtado-Bagès, Ciro Rivera-Casas, Gunnar Knobloch, Roberto Malinverni, Vanesa Valero, Michelle M Leger, Jesús García, Jerome Basquin, Marta Gómez de Cedrón and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature structural & molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 4 countries.

Iva GuberovicCancer and Leukaemia Epigenetics and Biology Program, Josep Carreras Leukaemia Research Institute, Badalona, Spain.ORCID http://orcid.org/0000-0003-3490-7447
Sarah Hurtado-BagèsCancer and Leukaemia Epigenetics and Biology Program, Josep Carreras Leukaemia Research Institute, Badalona, Spain.
Ciro Rivera-CasasEnvironmental Epigenetics Laboratory, Institute of Environment, Florida International University, Miami, FL, USA.
Gunnar KnoblochBiomedical Center, Department of Physiological Chemistry, LMU Munich, Martinsried Planegg, Germany.
Roberto MalinverniCancer and Leukaemia Epigenetics and Biology Program, Josep Carreras Leukaemia Research Institute, Badalona, Spain.
Vanesa ValeroCancer and Leukaemia Epigenetics and Biology Program, Josep Carreras Leukaemia Research Institute, Badalona, Spain.
Michelle M LegerInstitute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra), Barcelona, Spain.ORCID http://orcid.org/0000-0001-5500-5480
Jesús GarcíaInstitute for Research in Biomedicine, The Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID http://orcid.org/0000-0003-2961-9790
Jerome BasquinMax Planck Institute of Biochemistry, Department of Structural Cell Biology, Martinsried Planegg, Germany.
Marta Gómez de CedrónMolecular Oncology Group, IMDEA Food Institute, CEI UAM+CSIC, Madrid, Spain.ORCID http://orcid.org/0000-0002-0894-970X
Marta Frigolé-VivasInstitute for Research in Biomedicine, The Barcelona Institute of Science and Technology, Barcelona, Spain.
Manjinder S CheemaDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada.
Ainhoa PérezCancer and Leukaemia Epigenetics and Biology Program, Josep Carreras Leukaemia Research Institute, Badalona, Spain.
Juan AusióDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada.
Ana Ramírez de MolinaMolecular Oncology Group, IMDEA Food Institute, CEI UAM+CSIC, Madrid, Spain.
Xavier SalvatellaInstitute for Research in Biomedicine, The Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID http://orcid.org/0000-0002-8371-4185
Iñaki Ruiz-TrilloInstitute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra), Barcelona, Spain.
Jose M Eirin-LopezEnvironmental Epigenetics Laboratory, Institute of Environment, Florida International University, Miami, FL, USA.
Andreas G LadurnerBiomedical Center, Department of Physiological Chemistry, LMU Munich, Martinsried Planegg, Germany.
Marcus BuschbeckCancer and Leukaemia Epigenetics and Biology Program, Josep Carreras Leukaemia Research Institute, Badalona, Spain. mbuschbeck@carrerasresearch.org.ORCID http://orcid.org/0000-0002-3218-4567
Josep Carreras Leukaemia Research Institute · ESEisbach Bio (Germany) · DEFlorida International University · USInstitució Catalana de Recerca i Estudis Avançats · ESInstitute for Research in Biomedicine · ESMadrid Institute for Advanced Studies · ESUniversity of Victoria · CAMax Planck Institute of Biochemistry · DEUniversitat Pompeu Fabra · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NAD metabolism is essential for all forms of life. Compartmental regulation of NAD

Indexed as

Cell NucleusChromatinDNA RepairEnergy MetabolismEukaryotaHistonesHumansNADPoly (ADP-Ribose) Polymerase-1ChromatinHistonesMACROH2A1 protein, humanNADPARP1 protein, humanPoly (ADP-Ribose) Polymerase-1

Identifiers

PMID34887560
OpenAlexW4200270594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.