ArticleScientific reports2021
Incidence and risk factor of allergic contact dermatitis to 2-octyl cyanoacrylate and n-butyl cyanoacrylate topical skin adhesives.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Cyanoacrylate glue reactions: A systematic review, cases, and proposed mechanisms.Journal of vascular surgery. Venous and lymphatic disorders · 2023Pooled it
- Comparing contact dermatitis due to tissue adhesives in port-site closure.Surgical endoscopy · 2026Trial
- Allergic Contact Dermatitis to 2-Octyl Cyanoacrylate After Total Joint Arthroplasty: A Single-Surgeon Case Series.Arthroplasty today · 2026Article
- Wound Dressing and Postoperative Complications Following Breast Reduction: A Retrospective Study of 250 Patients.Aesthetic surgery journal. Open forum · 2026Article
- Sensitization Patterns to Cyanoacrylate-Based Surgical Glues.Contact dermatitis · 2025Article
- Diagnosis and Treatment of Perioperative Allergic Complications: A Practical Review.Plastic and reconstructive surgery. Global open · 2024Review
- Article
- Comparative Evaluation of the Aesthetic Outcomes of Octyl-2-Cyanoacrylate Skin Adhesive and Ethilon Suture in Maxillofacial Surgery - A Randomised Clinical Study.Annals of maxillofacial surgeryArticle
- Attached Oral Mucosal Wound Closure using Blue Glue - A Prospective Clinical Study.Annals of maxillofacial surgeryArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the use of topical skin adhesives has increased as an alternative to conventional skin closure methods, studies on the incidence and risk factors of allergic contact dermatitis (ACD) to topical skin adhesives have been limited. The purpose of this study was to investigate the incidence and risk factors of ACD after the use of 2-octyl cyanoacrylate and n-butyl cyanoacrylate topical skin adhesives. We retrospectively reviewed 1145 patients (739 patients with 2-octyl cyanoacrylate and 406 patients with n-butyl cyanoacrylate) who underwent skin closure with topical skin adhesives. Variables suspected to correlate with ACD were retrieved from medical records and analyzed to determine risk factors. The incidence of ACD from the use of 2-octyl cyanoacrylate and n-butyl cyanoacrylate topical skin adhesives was 2.7% and 2.2%, respectively. There was no statistically significant difference in the incidence between the two ingredients. In logistic regression analysis, none of the variables were found to increase the risk of ACD in both 2-octyl cyanoacrylate and n-butyl cyanoacrylate topical skin adhesives. As ACD occurs without risk factors in 2-3% of patients who used 2-octyl cyanoacrylate or n-butyl cyanoacrylate topical skin adhesives, clinicians and patients should be aware of these facts before using topical skin adhesives.
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