Evidence map›Paper›PMID 34886841›Full record

ArticleBMC psychiatry2021

Anxiety severity and cognitive function in primary care patients with anxiety disorder: a cross-sectional study.

Jenny Nyberg, Malin Henriksson, Alexander Wall, Torbjörn Vestberg, Maria Westerlund, Marion Walser, Robert Eggertsen, Louise Danielsson, H Georg Kuhn, N David Åberg and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Jenny Nyberg *Section for Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Box 436, SE-405 30, Gothenburg, Sweden. jenny.nyberg@neuro.gu.se.
Malin Henriksson *School of Public Health and Community Medicine/Primary Health Care, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Box 454, SE-405 30, Gothenburg, Sweden.
Alexander WallDepartment of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Box 428, SE-405 30, Gothenburg, Sweden.
Torbjörn VestbergDepartment of Clinical Neuroscience, Karolinska Institutet, K8 Clinical Neuroscience, K8 Neuro Ingvar, SE-171 77, Stockholm, Sweden.
Maria WesterlundRegion Västra Götaland, Regionhälsan, Gothenburg, Sweden.
Marion WalserDepartment of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Box 428, SE-405 30, Gothenburg, Sweden.
Robert EggertsenSchool of Public Health and Community Medicine/Primary Health Care, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Box 454, SE-405 30, Gothenburg, Sweden.
Louise DanielssonDepartment of Health and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Box 455, SE-405 30, Gothenburg, Sweden.
H Georg KuhnSection for Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Box 436, SE-405 30, Gothenburg, Sweden.
N David ÅbergDepartment of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Box 428, SE-405 30, Gothenburg, Sweden.
Margda WaernDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Box 436, SE-405 30, Gothenburg, Sweden.
Maria ÅbergSchool of Public Health and Community Medicine/Primary Health Care, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Box 454, SE-405 30, Gothenburg, Sweden.
University of Gothenburg · SERegion Västra Götaland · SESahlgrenska University Hospital · SEAngered Hospital · SEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeficits in cognitive performance are reported in patients with anxiety disorders, but research is limited and inconsistent. We aimed to investigate cross-sectional associations between cognitive function, with focus on executive function, and anxiety severity in primary care patients diagnosed with anxiety disorders.

methods189 Swedish patients aged 18-65 years (31% men) with anxiety disorders diagnosed according to Mini International Neuropsychiatric Interview were included. Severity of anxiety was assessed using Beck Anxiety Inventory self-assessment scale. Digit span, block design and matrix reasoning tests from the Wechsler Adult Intelligence Scale IV, and the design fluency test from the Delis-Kaplan Executive Function System were used. Multivariable linear regression models were applied to investigate the relationship of anxiety severity and cognitive functioning. Comparisons were also performed to a normed non-clinical population, using the Wilcoxon signed rank test.

resultsMore severe anxiety was associated with lower digit span test scores (R

conclusionsSeverity of anxiety among patients with anxiety disorder was associated with executive functions related to working memory, independently of comorbid major depression, but not with lower fluid intelligence. A further understanding of the executive behavioral control in patients with anxiety could allow for more tailored treatment strategies including medication, therapy and interventions targeted to improve specific cognitive domains.

Indexed as

CognitionMajor Depressive DisorderAdultAnxietyAnxiety DisordersCross-Sectional StudiesExecutive FunctionFemaleHumansMaleNeuropsychological TestsPrimary Health CareAnxiety disorderCognitive functionExecutive functionPrimary careWechsler adult intelligence scale

Identifiers

PMID34886841
PMCPMC8662874
OpenAlexW4200159506

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.