Evidence map›Paper›PMID 34886756›Full record

ReviewHuman vaccines & immunotherapeutics2022

Plasma therapy: a passive resistance against the deadliest.

Anita Hansda, Debarati Biswas, Aishwarya Bhatta, Nishant Chakravorty, Gayatri Mukherjee

Open access · bronzeAbstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Special focus issue: passive immunization.Human vaccines & immunotherapeutics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anita HansdaSchool of Medical Science and Technology, Indian Institute of Technology Kharagpur, India.
Debarati BiswasSchool of Medical Science and Technology, Indian Institute of Technology Kharagpur, India.
Aishwarya BhattaSchool of Medical Science and Technology, Indian Institute of Technology Kharagpur, India.
Nishant ChakravortySchool of Medical Science and Technology, Indian Institute of Technology Kharagpur, India.
Gayatri MukherjeeSchool of Medical Science and Technology, Indian Institute of Technology Kharagpur, India.ORCID 0000-0003-3199-7213
Indian Institute of Technology Kharagpur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Convalescent plasma therapy provides a useful therapeutic tool to treat infectious diseases, especially where no specific therapeutic strategies have been identified. The ongoing pandemic puts back the spotlight on this age-old method as a viable treatment option. In this review, we discuss the usage of this therapy in different diseases including COVID-19, and the possible mechanisms of action. The current review also discusses the progress of therapeutic applications of blood-derivatives, from the simple transfer of immunized animal sera, to the more target-specific intravenous administration of human immunoglobulins from a pool of convalescent individuals, in both infectious and non-infectious diseases of various etiologies.

Indexed as

COVID-19SARS-CoV-2AnimalsAntibodies, NeutralizingAntibodies, ViralCOVID-19 SerotherapyImmunization, PassivePandemicsAntibodies, NeutralizingAntibodies, ViralConvalescent plasmaintravenous immunoglobulin (IVIG)neutralizing antibodies (NAbs)

Identifiers

PMID34886756
PMCPMC9116411
OpenAlexW4200468339

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.