Evidence map›Paper›PMID 34886573›Full record

ArticleInternational journal of environmental research and public health2021

Dental-Plaque Decontamination around Dental Brackets Using Antimicrobial Photodynamic Therapy: An In Vitro Study.

Daliana-Emanuela Mocuta Bojoga, Mariana Ioana Miron, Elena Hogea, Cornelia Muntean, Darinca Carmen Todea

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daliana-Emanuela Mocuta BojogaDepartment of Oral Rehabilitation and Dental Emergencies, Faculty of Dentistry, "Victor Babes" University of Medicine and Pharmacy, P-ta Eftimie Murgu 2, 300041 Timisoara, Romania.
Mariana Ioana MironDepartment of Oral Rehabilitation and Dental Emergencies, Faculty of Dentistry, "Victor Babes" University of Medicine and Pharmacy, P-ta Eftimie Murgu 2, 300041 Timisoara, Romania.ORCID 0000-0002-4904-0885
Elena HogeaDepartment of Microbiology, Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Victor Babes Street, No. 16, 300226 Timisoara, Romania.
Cornelia MunteanFaculty of Industrial Chemistry and Environmental Engineering, Politehnica University Timisoara, Vasile Parvan Street, No. 6, 300223 Timisoara, Romania.ORCID 0000-0002-1415-8541
Darinca Carmen TodeaDepartment of Oral Rehabilitation and Dental Emergencies, Faculty of Dentistry, "Victor Babes" University of Medicine and Pharmacy, P-ta Eftimie Murgu 2, 300041 Timisoara, Romania.
Victor Babeș University of Medicine and Pharmacy Timișoara · ROPolytechnic University of Timişoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn orthodontic therapy, the enamel around brackets is very susceptible to bacterial-plaque retention, which represents a risk factor for dental tissues. The aim of this study was to evaluate the effect of methylene blue and a chlorophyllin-phycocyanin mixture, used with and without light activation, in contrast with a 2% chlorhexidine solution, on Streptococcus mutans colonies.

methodsTwenty caries-free human extracted teeth were randomized into five groups. A Streptococcus mutans suspension was inoculated on teeth in groups B, C, D, and E (A was the positive-control group). Bacterial colonies from groups C, D, and E (B was the negative-control group) were subjected to photosensitizers and 2% chlorhexidine solution. For groups C and D, a combined therapy consisting of photosensitizer and light activation was performed. The Streptococcus mutans colonies were counted, and smears were examined with an optical microscope. Two methods of statistical analysis, unidirectional analysis of variance and the Tukey-Kramer test, were used to evaluate the results.

resultsA statistically significant reduction in bacterial colonies was detected after the combined therapy was applied for groups C and D, but the most marked bacterial reduction was observed for group D, where a laser-activated chlorophyll-phycocyanin mixture was used.

conclusionsPhotodynamic therapy in combination with methylene blue or chlorophyllin-phycocyanin mixture sensitizers induces a statistically significant decrease in the number of bacterial colonies.

Indexed as

Anti-Infective AgentsPhotochemotherapyDecontaminationHumansPhotosensitizing AgentsStreptococcus mutansAnti-Infective AgentsPhotosensitizing Agentsantimicrobial photodynamic therapybracketchlorophyllin–phycocyaninmethylene blueStreptococcus mutans

Identifiers

PMID34886573
PMCPMC8657741
OpenAlexW4200465149

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.