Evidence map›Paper›PMID 34886378›Full record

ArticleInternational journal of environmental research and public health2021

Validation of a Novel Predictive Algorithm for Kidney Failure in Patients Suffering from Chronic Kidney Disease: The Prognostic Reasoning System for Chronic Kidney Disease (PROGRES-CKD).

Francesco Bellocchio, Caterina Lonati, Jasmine Ion Titapiccolo, Jennifer Nadal, Heike Meiselbach, Matthias Schmid, Barbara Baerthlein, Ulrich Tschulena, Markus Schneider, Ulla T Schultheiss and 6 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Chronic kidney disease-associated pruritus (CKD-aP) is associated with worse quality of life and increased healthcare utilization among dialysis patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  12. Data Science in Healthcare: COVID-19 and Beyond.International journal of environmental research and public health · 2022
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Francesco BellocchioClinical & Data Intelligence Systems-Advanced Analytics, Fresenius Medical Care Deutschland GmbH, 26020 Vaiano Cremasco, Italy.
Caterina LonatiCenter for Preclinical Research, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0001-7855-7851
Jasmine Ion TitapiccoloClinical & Data Intelligence Systems-Advanced Analytics, Fresenius Medical Care Deutschland GmbH, 26020 Vaiano Cremasco, Italy.
Jennifer NadalDepartment of Medical Biometry, Informatics, and Epidemiology (IMBIE), Faculty of Medicine, University of Bonn, 53113 Bonn, Germany.
Heike MeiselbachDepartment of Nephrology and Hypertension, Friedrich-Alexander University of Erlangen-Nürnberg, 91054 Erlangen, Germany.
Matthias SchmidDepartment of Medical Biometry, Informatics, and Epidemiology (IMBIE), Faculty of Medicine, University of Bonn, 53113 Bonn, Germany.
Barbara BaerthleinMedical Centre for Information and Communication Technology (MIK), University Hospital Erlangen, 91054 Erlangen, Germany.
Ulrich TschulenaFresenius Medical Care, Deutschland GmbH, 61352 Bad Homburg, Germany.
Markus SchneiderDepartment of Medical Biometry, Informatics, and Epidemiology (IMBIE), Faculty of Medicine, University of Bonn, 53113 Bonn, Germany.
Ulla T SchultheissInstitute of Genetic Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, 79085 Freiburg, Germany.ORCID 0000-0002-7541-5310
Carlo BarbieriFresenius Medical Care, Deutschland GmbH, 61352 Bad Homburg, Germany.
Christoph MooreFresenius Medical Care, Deutschland GmbH, 61352 Bad Homburg, Germany.
Sonja SteppanFresenius Medical Care, Deutschland GmbH, 61352 Bad Homburg, Germany.
Kai-Uwe EckardtDepartment of Nephrology and Hypertension, Friedrich-Alexander University of Erlangen-Nürnberg, 91054 Erlangen, Germany.
Stefano StuardFresenius Medical Care, Deutschland GmbH, 61352 Bad Homburg, Germany.
Luca NeriClinical & Data Intelligence Systems-Advanced Analytics, Fresenius Medical Care Deutschland GmbH, 26020 Vaiano Cremasco, Italy.ORCID 0000-0001-5438-1329
Fresenius Medical Care (Germany) · DEUniversity of Bonn · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversitätsklinikum Erlangen · DEUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current equation-based risk stratification algorithms for kidney failure (KF) may have limited applicability in real world settings, where missing information may impede their computation for a large share of patients, hampering one from taking full advantage of the wealth of information collected in electronic health records. To overcome such limitations, we trained and validated the Prognostic Reasoning System for Chronic Kidney Disease (PROGRES-CKD), a novel algorithm predicting end-stage kidney disease (ESKD). PROGRES-CKD is a naïve Bayes classifier predicting ESKD onset within 6 and 24 months in adult, stage 3-to-5 CKD patients. PROGRES-CKD trained on 17,775 CKD patients treated in the Fresenius Medical Care (FMC) NephroCare network. The algorithm was validated in a second independent FMC cohort (

Indexed as

Kidney Failure, ChronicRenal InsufficiencyRenal Insufficiency, ChronicAlgorithmsBayes TheoremDisease ProgressionHumansPrognosisRisk Assessmentartificial intelligencechronic kidney disease (CKD)end-stage kidney disease (ESKD)kidney replacement therapy (KRT)machine learningnaïve Bayes classifiersprecision medicinerisk prediction

Identifiers

PMID34886378
PMCPMC8656741
OpenAlexW3216545748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.