Evidence map›Paper›PMID 34886275›Full record

SynthesisInternational journal of environmental research and public health2021

Per- and Polyfluoroalkyl Substances (PFAS) in Integrated Crop-Livestock Systems: Environmental Exposure and Human Health Risks.

Gaurav Jha, Vanaja Kankarla, Everald McLennon, Suman Pal, Debjani Sihi, Biswanath Dari, Dawson Diaz, Mallika Nocco

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 134 citations in OpenAlex.

  1. Dietary and social predictors of PFAS exposure in Hispanic children from Northern Virginia.Journal of exposure science & environmental epidemiology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Impact of GenX onJournal of agricultural and food chemistry · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Carbon footprint of Pars plana vitrectomies in rhegmatogenous retinal detachment in Germany between 2013 and 2023 - A cohort study of fluorinated gas emissions.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Gaurav JhaDepartment of Land, Air and Water Resources, University of California, Davis, CA 95616, USA.ORCID 0000-0002-7317-017X
Vanaja KankarlaDepartment of Soil and Crop Sciences, Texas A&M University, College Station, TX 77843, USA.
Everald McLennonDepartment of Crop and Soil Science, Oregon State University, Klamath Falls, OR 97603, USA.
Suman PalDepartment of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87106, USA.ORCID 0000-0002-2051-9788
Debjani SihiDepartment of Environmental Sciences, Emory University, Atlanta, GA 30322, USA.
Biswanath DariAgricultural and Natural Resources, Cooperative Extension at North Carolina Agricultural and Technical State University, Greensboro, NC 27411, USA.
Dawson DiazDepartment of Land, Air and Water Resources, University of California, Davis, CA 95616, USA.
Mallika NoccoDepartment of Land, Air and Water Resources, University of California, Davis, CA 95616, USA.ORCID 0000-0002-6067-8759
University of California, Davis · USEmory University · USNorth Carolina Agricultural and Technical State University · USOregon State University · USTexas A&M University · USUniversity of New Mexico · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Per- and polyfluoroalkyl substances (PFAS) are highly persistent synthetic organic contaminants that can cause serious human health concerns such as obesity, liver damage, kidney cancer, hypertension, immunotoxicity and other human health issues. Integrated crop-livestock systems combine agricultural crop production with milk and/or meat production and processing. Key sources of PFAS in these systems include firefighting foams near military bases, wastewater sludge and industrial discharge. Per- and polyfluoroalkyl substances regularly move from soils to nearby surface water and/or groundwater because of their high mobility and persistence. Irrigating crops or managing livestock for milk and meat production using adjacent waters can be detrimental to human health. The presence of PFAS in both groundwater and milk have been reported in dairy production states (e.g., Wisconsin and New Mexico) across the United States. Although there is a limit of 70 parts per trillion of PFAS in drinking water by the U.S. EPA, there are not yet regional screening guidelines for conducting risk assessments of livestock watering as well as the soil and plant matrix. This systematic review includes (i) the sources, impacts and challenges of PFAS in integrated crop-livestock systems, (ii) safety measures and protocols for sampling soil, water and plants for determining PFAS concentration in exposed integrated crop-livestock systems and (iii) the assessment, measurement and evaluation of human health risks related to PFAS exposure.

Indexed as

FluorocarbonsGroundwaterWater Pollutants, ChemicalAnimalsEnvironmental ExposureHumansLivestockFluorocarbonsWater Pollutants, Chemicalchronic kidney diseaseenvironmental justiceexposure pathwayfoaming agentforever chemicalsgroundwater contaminantslivestock contaminationsremediationrenal dysfunction

Identifiers

PMID34886275
PMCPMC8657007
OpenAlexW3217366317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.