Evidence map›Paper›PMID 34886126›Full record

ReviewInternational journal of environmental research and public health2021

Microalgae as a Source of Mycosporine-like Amino Acids (MAAs); Advances and Future Prospects.

Subhisha Raj, Anusree M Kuniyil, Arathi Sreenikethanam, Poornachandar Gugulothu, Rajesh Banu Jeyakumar, Amit K Bajhaiya

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
10.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Article
  3. Cyanobacteria Under UV Radiation: General Insights into Stress Responses.International journal of molecular sciences · 2025
    Review
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  5. Review
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  8. Article
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  11. Article
  12. Photoprotective Effects of Yeast Pulcherrimin.Molecules (Basel, Switzerland) · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Subhisha RajAlgal Biotechnology Lab, Department of Microbiology, Central University of Tamil Nadu, Thiruvarur 610104, Tamil Nadu, India.ORCID 0000-0002-9651-588X
Anusree M KuniyilAlgal Biotechnology Lab, Department of Microbiology, Central University of Tamil Nadu, Thiruvarur 610104, Tamil Nadu, India.ORCID 0000-0003-0297-1284
Arathi SreenikethanamAlgal Biotechnology Lab, Department of Microbiology, Central University of Tamil Nadu, Thiruvarur 610104, Tamil Nadu, India.
Poornachandar GugulothuDepartment of Life Sciences, Central University of Tamil Nadu, Thiruvarur 610104, Tamil Nadu, India.ORCID 0000-0001-7185-9507
Rajesh Banu JeyakumarDepartment of Life Sciences, Central University of Tamil Nadu, Thiruvarur 610104, Tamil Nadu, India.
Amit K BajhaiyaAlgal Biotechnology Lab, Department of Microbiology, Central University of Tamil Nadu, Thiruvarur 610104, Tamil Nadu, India.ORCID 0000-0002-9912-4278
Central University of Tamil Nadu · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycosporine-like amino acids (MAAs), are secondary metabolites, first reported in 1960 and found to be associated with the light-stimulated sporulation in terrestrial fungi. MAAs are nitrogenous, low molecular weight, water soluble compounds, which are highly stable with cyclohexenone or cycloheximine rings to store the free radicals. Microalgae are considered as a good source of different kinds of MAAs, which in turn, has its own applications in various industries due to its UV absorbing, anti-oxidant and therapeutic properties. Microalgae can be easily cultivated and requires a very short generation time, which makes them environment friendly source of biomolecules such as mycosporine-like amino acids. Modifying the cultural conditions along withmanipulation of genes associated with mycosporine-like amino acids biosynthesis can help to enhance MAAs synthesis and, in turn, can make microalgae suitable bio-refinery for large scale MAAs production. This review focuses on properties and therapeutic applications of mycosporine like amino acids derived from microalgae. Further attention is drawn on various culture and genetic engineering approaches to enhance the MAAs production in microalgae.

Indexed as

Amino AcidsMicroalgaeAntioxidantsUltraviolet RaysAmino AcidsAntioxidantsanti-cancer activitybio-refinerygenetic engineeringmicroalgaemycosporine-like amino acidsphotoprotective activity

Identifiers

PMID34886126
PMCPMC8656575
OpenAlexW3216857338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.