ArticleMolecules (Basel, Switzerland)2021
Copper-Catalyzed Ring-Opening Reactions of Alkyl Aziridines with B
Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Copper-Catalyzed One-Pot Functionalization of Styrenes: Application toward Pharmaceutically Relevant Phenylethylamine Triazole Scaffolds.The Journal of organic chemistry · 2025Article
- Reactions of Benzylboronate Nucleophiles.Synthesis · 2023Article
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Authors and funding
7 authors.
Funding
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Abstract
The possibility to form new C-B bonds with aziridines using diboron derivatives continues to be a particularly challenging field in view of the direct preparation of functionalized β-aminoboronates, which are important compounds in drug discovery, being a bioisostere of β-aminoacids. We now report experimental and computational data that allows the individuation of the structural requisites and of reaction conditions necessary to open alkyl aziridines using bis(pinacolate)diboron (B
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Registered trials
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