Evidence map›Paper›PMID 34885972›Full record

ArticleMolecules (Basel, Switzerland)2021

Magnolol and Honokiol Inhibited the Function and Expression of BCRP with Mechanism Exploration.

Chung-Ping Yu, Pei-Ying Li, Szu-Yu Chen, Shiuan-Pey Lin, Yu-Chi Hou

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chung-Ping YuSchool of Pharmacy, College of Pharmacy, China Medical University, Taichung 406040, Taiwan.
Pei-Ying LiSchool of Pharmacy, College of Pharmacy, China Medical University, Taichung 406040, Taiwan.
Szu-Yu ChenSchool of Pharmacy, College of Pharmacy, China Medical University, Taichung 406040, Taiwan.
Shiuan-Pey LinSchool of Pharmacy, College of Pharmacy, China Medical University, Taichung 406040, Taiwan.
Yu-Chi HouSchool of Pharmacy, College of Pharmacy, China Medical University, Taichung 406040, Taiwan.
China Medical University · TW

Funding

China Medical University CMU109-MF-20China Medical University Hospital DMR-108-146Ministry of Science and Technology MOST 108-2320-B-039-041-MY3
6 · The paper itself

Abstract

Breast cancer resistance protein (BCRP), one of the ATP-binding cassette (ABC) transporters, was associated with the multidrug resistance (MDR) of chemotherapy. Magnolol (MN) and honokiol (HK) are major bioactive polyphenols of

Indexed as

Allyl CompoundsAnimalsATP Binding Cassette Transporter, Subfamily G, Member 2Biphenyl CompoundsCell SurvivalDogsDrug Resistance, MultipleDrug Resistance, NeoplasmErbB ReceptorsLignansMadin Darby Canine Kidney CellsMagnoliaNeoplasm ProteinsPhenolsPhosphatidylinositol 3-KinasesPhosphorylationAllyl CompoundsATP Binding Cassette Transporter, Subfamily G, Member 2Biphenyl CompoundsErbB ReceptorshonokiolLignansmagnololNeoplasm ProteinsPhenolsPhosphatidylinositol 3-KinasesPlant ExtractsPolyphenolsBCRPEGFRhonokiolmagnololMDR

Identifiers

PMID34885972
PMCPMC8659015
OpenAlexW4200585632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.