Evidence map›Paper›PMID 34885936›Full record

ArticleMolecules (Basel, Switzerland)2021

The Anthelmintic Quassinoids Ailanthone and Bruceine a Induce Infertility in the Model Organism

Nicola Knetzger, Viktoria Bachtin, Susanne Lehmann, Andreas Hensel, Eva Liebau, Fabian Herrmann

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nicola KnetzgerInstitute for Pharmaceutical Biology and Phytochemistry (IPBP), University of Muenster, Pharma Campus, Corrensstrasse 48, D-48149 Muenster, Germany.
Viktoria BachtinInstitute for Pharmaceutical Biology and Phytochemistry (IPBP), University of Muenster, Pharma Campus, Corrensstrasse 48, D-48149 Muenster, Germany.
Susanne LehmannInstitute for Pharmaceutical Biology and Phytochemistry (IPBP), University of Muenster, Pharma Campus, Corrensstrasse 48, D-48149 Muenster, Germany.
Andreas HenselInstitute for Pharmaceutical Biology and Phytochemistry (IPBP), University of Muenster, Pharma Campus, Corrensstrasse 48, D-48149 Muenster, Germany.
Eva LiebauDepartment of Molecular Physiology, Institute of Animal Physiology, University of Muenster, Schlossplatz 8, D-48143 Muenster, Germany.
Fabian HerrmannInstitute for Pharmaceutical Biology and Phytochemistry (IPBP), University of Muenster, Pharma Campus, Corrensstrasse 48, D-48149 Muenster, Germany.
University of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In continuation of the search for new anthelmintic natural products, the study at hand investigated the nematicidal effects of the two naturally occurring quassinoids ailanthone and bruceine A against the reproductive system of the model nematode

Indexed as

AnimalsAnthelminticsApoptosisCaenorhabditis elegansGonadsInfertilityMaleQuassinsailanthoneAnthelminticsbruceine AQuassinsailanthoneanthelmintic natural productsatomic force microscopybruceine ACaenorhabditis eleganspolyethylene glycol embeddingquassinoidultramicrotomyultrastructural morphology

Identifiers

PMID34885936
PMCPMC8659173
OpenAlexW4200590897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.