Ultrasonication Improves Solid Phase Synthesis of Peptides Specific for Fibroblast Growth Factor Receptor and for the Protein-Protein Interface RANK-TRAF6.
Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 5 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
8 authors at 1 institution in 1 country.
Rúben D M SilvaCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, CTN, Estrada Nacional 10 (km 139.7), Bobadela, 2695-066 Loures, Portugal.ORCID 0000-0003-3665-9571
João Franco MachadoCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, CTN, Estrada Nacional 10 (km 139.7), Bobadela, 2695-066 Loures, Portugal.ORCID 0000-0003-3741-2386
Kyle GonçalvesCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, CTN, Estrada Nacional 10 (km 139.7), Bobadela, 2695-066 Loures, Portugal.ORCID 0000-0001-5160-1357
Francisco M LucasCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, CTN, Estrada Nacional 10 (km 139.7), Bobadela, 2695-066 Loures, Portugal.
Salete BatistaCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, CTN, Estrada Nacional 10 (km 139.7), Bobadela, 2695-066 Loures, Portugal.
Rita MeloCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, CTN, Estrada Nacional 10 (km 139.7), Bobadela, 2695-066 Loures, Portugal.ORCID 0000-0003-1056-1007
Tânia S MoraisCentro de Química Estrutural and Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal.ORCID 0000-0003-0233-8243
João D G CorreiaCentro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, CTN, Estrada Nacional 10 (km 139.7), Bobadela, 2695-066 Loures, Portugal.ORCID 0000-0002-7847-4906
University of Lisbon · PT
Funding
Fundação para a Ciência e Tecnologia CEECIND/00630/2017Fundação para a Ciência e Tecnologia DFA/BD/4978/2020Fundação para a Ciência e Tecnologia PTDC/QUI-NUC/30147/2017Fundação para a Ciência e Tecnologia PTDC/QUI-QIN/0146/2020Fundação para a Ciência e Tecnologia SFRH/BD/135915/2018Fundação para a Ciência e Tecnologia UIDB/00100/2020Fundação para a Ciência e Tecnologia UID/Multi/04349/2020
6 · The paper itself
Abstract
Considering our interest in the use of peptides as potential target-specific drugs or as delivery vectors of metallodrugs for various biomedical applications, it is crucial to explore improved synthetic methodologies to accomplish the highest peptide crude purity in the shortest time possible. Therefore, we compared "classical" fluorenylmethoxycarbonyl (Fmoc)-solid phase peptide synthesis (SPPS) with ultrasound(US)-assisted SPPS based on the preparation of three peptides, namely the fibroblast growth factor receptor 3(FGFR3)-specific peptide Pep1 (VSPPLTLGQLLS-NH
Indexed as
HumansPeptidesReceptor Activator of Nuclear Factor-kappa BReceptors, Fibroblast Growth FactorSolid-Phase Synthesis TechniquesSonicationTNF Receptor-Associated Factor 6PeptidesReceptor Activator of Nuclear Factor-kappa BReceptors, Fibroblast Growth FactorTNF Receptor-Associated Factor 6difficult sequencespeptidessolid phase synthesissonochemistry and ultrasound
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Ultrasonication Improves Solid Phase Synthesis of Peptides Specific for Fibroblast Growth Factor Receptor and for the Protein-Protein Interface RANK-TRAF6. · full record | OpenQuestion