Evidence map›Paper›PMID 34885915›Full record

ArticleMolecules (Basel, Switzerland)2021

Encapsulation of Metronidazole in Biocompatible Macrocycles and Structural Characterization of Its Nano Spray-Dried Nanostructured Composite.

Mirella Mirankó, Mónika Megyesi, Zsombor Miskolczy, Judit Tóth, Tivadar Feczkó, László Biczók

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mirella MirankóResearch Institute of Biomolecular and Chemical Engineering, Faculty of Engineering, University of Pannonia, Egyetem St. 10, 8200 Veszprém, Hungary.
Mónika MegyesiResearch Centre for Natural Sciences, Institute of Materials and Environmental Chemistry, Eötvös Loránd Research Network (ELKH), P.O. Box 286, 1519 Budapest, Hungary.ORCID 0000-0001-5080-7310
Zsombor MiskolczyResearch Centre for Natural Sciences, Institute of Materials and Environmental Chemistry, Eötvös Loránd Research Network (ELKH), P.O. Box 286, 1519 Budapest, Hungary.ORCID 0000-0003-2259-5052
Judit TóthResearch Institute of Biomolecular and Chemical Engineering, Faculty of Engineering, University of Pannonia, Egyetem St. 10, 8200 Veszprém, Hungary.
Tivadar FeczkóResearch Institute of Biomolecular and Chemical Engineering, Faculty of Engineering, University of Pannonia, Egyetem St. 10, 8200 Veszprém, Hungary.
László BiczókResearch Centre for Natural Sciences, Institute of Materials and Environmental Chemistry, Eötvös Loránd Research Network (ELKH), P.O. Box 286, 1519 Budapest, Hungary.ORCID 0000-0003-2568-5942
Institute of Materials and Environmental Chemistry · HUUniversity of Pannonia · HU

Funding

National Research, Development and Innovation Fund of Hungary GINOP-2.2.1-15-2016-00023National Research, Development and Innovation Fund of Hungary TKP2020-IKA-07National Research, Development and Innovation Office, Hungary K123995
6 · The paper itself

Abstract

Due to the great potential of biocompatible cucurbit[7]uril (CB7) and 4-sulfonatocalix[4]arene (SCX4) macrocycles in drug delivery, the confinement of the pharmaceutically important metronidazole as an ionizable model drug has been systematically studied in these cavitands. Absorption and fluorescence spectroscopic measurements gave 1.9 × 10

Indexed as

Anti-Infective AgentsBridged-Ring CompoundsCalixarenesCucurbit(n)urilsDrug CarriersDrug Delivery SystemsImidazolesMacrocyclic CompoundsMetronidazoleNanostructuresPhenolsSpray DryingAnti-Infective AgentsBridged-Ring CompoundsCalixarenescucurbit(7)urilCucurbit(n)urilsDrug CarriersImidazolesMacrocyclic CompoundsMetronidazolePhenolsp-sulfonatocalix(4)arene4-sulfonatocalix[4]arenechitosancucurbit[7]urildrug deliveryhost–guest bindinginclusion complexmetronidazoleself-assemblyspray drying

Identifiers

PMID34885915
PMCPMC8659152
OpenAlexW4200499570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.