Evidence map›Paper›PMID 34885871›Full record

ArticleMolecules (Basel, Switzerland)2021

Preliminary Study of New Gallium-68 Radiolabeled Peptide Targeting NRP-1 to Detect Brain Metastases by Positron Emission Tomography.

Albert Moussaron, Valérie Jouan-Hureaux, Charlotte Collet, Julien Pierson, Noémie Thomas, Laurence Choulier, Nicolas Veran, Matthieu Doyen, Philippe Arnoux, Fatiha Maskali and 4 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  6. Preclinical evaluation ofEuropean journal of nuclear medicine and molecular imaging · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Albert MoussaronUniversité de Lorraine, CNRS, LRGP, F-54000 Nancy, France.
Valérie Jouan-HureauxUniversité de Lorraine, CNRS, CRAN, F-54000 Nancy, France.ORCID 0000-0003-1127-7067
Charlotte ColletNancyclotep Molecular Imaging Platform, F-54500 Vandœuvre-lès-Nancy, France.
Julien PiersonUniversité de Lorraine, CNRS, CRAN, F-54000 Nancy, France.
Noémie ThomasUniversité de Lorraine, CNRS, CRAN, F-54000 Nancy, France.
Laurence ChoulierUniversité de Strasbourg, CNRS, LBP, F-67000 Strasbourg, France.ORCID 0000-0003-1493-9775
Nicolas VeranNancyclotep Molecular Imaging Platform, F-54500 Vandœuvre-lès-Nancy, France.
Matthieu DoyenNancyclotep Molecular Imaging Platform, F-54500 Vandœuvre-lès-Nancy, France.
Philippe ArnouxUniversité de Lorraine, CNRS, LRGP, F-54000 Nancy, France.ORCID 0000-0002-6834-9597
Fatiha MaskaliNancyclotep Molecular Imaging Platform, F-54500 Vandœuvre-lès-Nancy, France.ORCID 0000-0002-3594-3960
Dominique DumasUniversité de Lorraine, CNRS, IMoPA, F-54000 Nancy, France.ORCID 0000-0002-2786-9633
Samir AcherarUniversité de Lorraine, CNRS, LCPM, F-54000 Nancy, France.ORCID 0000-0002-8776-1632
Muriel Barberi-HeyobUniversité de Lorraine, CNRS, CRAN, F-54000 Nancy, France.
Céline FrochotUniversité de Lorraine, CNRS, LRGP, F-54000 Nancy, France.ORCID 0000-0002-7659-3864
Centre National de la Recherche Scientifique · FRInserm · FR

Funding

Great East European Regional Development Fund (ERDF) and Contrat Plan Etat-Région (CPER) from French government, Great East Regional Council and Lorraine Université d'Excellence (LUE) 000
6 · The paper itself

Abstract

Due to their very poor prognosis and a fatal outcome, secondary brain tumors are one of the biggest challenges in oncology today. From the point of view of the early diagnosis of these brain micro- and macro-tumors, the sensitivity and specificity of the diagnostic tools constitute an obstacle. Molecular imaging, such as Positron Emission Tomography (PET), is a promising technique but remains limited in the search for cerebral localizations, given the commercially available radiotracers. Indeed, the [

Indexed as

Positron-Emission TomographyAnimalsBrain NeoplasmsCell Line, TumorCell ProliferationCell TrackingCerebellumFemaleGallium RadioisotopesHumansHuman Umbilical Vein Endothelial CellsNeuropilin-1PeptidesProtein BindingRadiopharmaceuticalsRatsGallium-68Gallium RadioisotopesNeuropilin-1PeptidesRadiopharmaceuticalsRecombinant ProteinsWaterbrain metastasesfluorescenceNRP-1peptideradiolabelingtargeting

Identifiers

PMID34885871
PMCPMC8659110
OpenAlexW3215827855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.