Evidence map›Paper›PMID 34885802›Full record

ReviewMolecules (Basel, Switzerland)2021

Recent Advances on the Halo- and Cyano-Trifluoromethylation of Alkenes and Alkynes.

Bo Fu, Jorge Escorihuela, Jianlin Han, Santos Fustero, Pablo Barrio, Mikiko Sodeoka, Shintaro Kawamura, Alexander Sorochinsky, Vadim A Soloshonok

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Featured Reviews in Organic Chemistry.Molecules (Basel, Switzerland) · 2023
    Article
  3. Ru(phen)ChemistryOpen · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bo FuJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.
Jorge EscorihuelaDepartamento de Química Orgánica, Universidad de Valencia, 46100 Valencia, Spain.ORCID 0000-0001-6756-0991
Jianlin HanJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.ORCID 0000-0002-3817-0764
Santos FusteroDepartamento de Química Orgánica, Universidad de Valencia, 46100 Valencia, Spain.
Pablo BarrioDepartamento de Química Orgánica e Inorgánica, Universidad de Oviedo, 33006 Oviedo, Spain.ORCID 0000-0001-7101-4037
Mikiko SodeokaRIKEN Center for Sustainable Resource Science, Catalysis and Integrated Research Group, and RIKEN Cluster for Pioneering Research, Synthetic Organic Chemistry Laboratory, Saitama 351-0198, Japan.
Shintaro KawamuraRIKEN Center for Sustainable Resource Science, Catalysis and Integrated Research Group, and RIKEN Cluster for Pioneering Research, Synthetic Organic Chemistry Laboratory, Saitama 351-0198, Japan.ORCID 0000-0002-7422-837X
Alexander SorochinskyV.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, The National Academy of Sciences of Ukraine, 02094 Kyiv, Ukraine.
Vadim A SoloshonokDepartment of Organic Chemistry I, Faculty of Chemistry, University of the Basque Country UPV/EHU, 20018 San Sebastián, Spain.ORCID 0000-0003-0681-4526

Funding

Agencia Estatal de Investigación CTQ2017-84249-PSpanish MINECO for a Ramón y Cajal contract RyC-2016-20951
6 · The paper itself

Abstract

Incorporation of fluorine into organic molecules is a well-established strategy in the design of advanced materials, agrochemicals, and pharmaceuticals. Among numerous modern synthetic approaches, functionalization of unsaturated bonds with simultaneous addition of trifluoromethyl group along with other substituents is currently one of the most attractive methods undergoing wide-ranging development. In this review article, we discuss the most significant contributions made in this area during the last decade (2012-2021). The reactions reviewed in this work include chloro-, bromo-, iodo-, fluoro- and cyano-trifluoromethylation of alkenes and alkynes.

Indexed as

alkenesalkynescyanotrifluoromethylationdifunctionalizationhalotrifluoromethylationsynthetic methods

Identifiers

PMID34885802
PMCPMC8659293

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.