Evidence map›Paper›PMID 34885700›Full record

ArticleMolecules (Basel, Switzerland)2021

Compounds from the Medicines for Malaria Venture Box Inhibit In Vitro Growth of

Mohamed Abdo Rizk, Shimaa Abd El-Salam El-Sayed, Mahmoud S Alkhoudary, Khalaf F Alsharif, Mohamed M Abdel-Daim, Ikuo Igarashi

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Pathogens and global health · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Antiparasitic activity of FLLL-32 against fourFrontiers in pharmacology · 2023
    Article
  8. Evaluation of theJournal of advanced veterinary and animal research · 2022
    Article
  9. Pomegranate (Journal of parasitology research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Mohamed Abdo RizkNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro 080-8555, Hokkaido, Japan.ORCID 0000-0002-5250-6172
Shimaa Abd El-Salam El-SayedNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro 080-8555, Hokkaido, Japan.
Mahmoud S AlkhoudaryFaculty of Pharmacy, Mansoura University, Mansoura 35516, Dakahlia, Egypt.
Khalaf F AlsharifDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.ORCID 0000-0002-8156-2069
Mohamed M Abdel-DaimPharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0002-4341-2713
Ikuo IgarashiNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro 080-8555, Hokkaido, Japan.
Mansoura University · EGObihiro University of Agriculture and Veterinary Medicine · JPSuez Canal University · EGTaif University · SA

Funding

Medicines for Malaria Venture Malaria Box not available
6 · The paper itself

Abstract

Babesiosis is an infectious disease with an empty drug pipeline. A search inside chemical libraries for novel potent antibabesial candidates may help fill such an empty drug pipeline. A total of 400 compounds (200 drug-like and 200 probe-like) from the Malaria Box were evaluated in the current study against the in vitro growth of

Indexed as

AnimalsAntiprotozoal AgentsAtovaquoneBabesiaBabesiosisBlood-Borne PathogensDiminazeneHumansImidocarbMalariaPlants, MedicinalAntiprotozoal AgentsAtovaquoneDiminazenediminazene aceturateImidocarbimidocarb dipropionateBabesia divergensin vitrolarge-scale screeningmalaria boxMMV006913

Identifiers

PMID34885700
PMCPMC8658764
OpenAlexW3215673461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.