Evidence map›Paper›PMID 34885686›Full record

ArticleMolecules (Basel, Switzerland)2021

Tetrandrine Suppresses Human Brain Glioblastoma GBM 8401/

Ching-Lung Liao, Yi-Shih Ma, Te-Chun Hsia, Yu-Cheng Chou, Jin-Cherng Lien, Shu-Fen Peng, Chao-Lin Kuo, Fei-Ting Hsu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Tetrandrine for Targeting Therapy Resistance in Cancer.Current topics in medicinal chemistry · 2024
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ching-Lung LiaoSchool of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung 40604, Taiwan.
Yi-Shih MaSchool of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung 840, Taiwan.
Te-Chun HsiaDepartment of Respiratory Therapy, China Medical University, Taichung 404, Taiwan.
Yu-Cheng ChouDepartment of Neurosurgery, Neurological Institute, Taichung Veterans General Hospital, Taichung 407, Taiwan.
Jin-Cherng LienSchool of Pharmacy, China Medical University, Taichung 404, Taiwan.ORCID 0000-0002-1211-0245
Shu-Fen PengDepartment of Medical Research, China Medical University Hospital, Taichung 404, Taiwan.
Chao-Lin KuoDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 404, Taiwan.
Fei-Ting HsuDepartment of Biological Science and Technology, China Medical University, Taichung 404, Taiwan.
China Medical University · TWE-Da Hospital · TWTri-Service General Hospital · TW

Funding

Ministry of Science and Technology (Taiwan) MOST 109-2314-B-039 -021-MY3
6 · The paper itself

Abstract

Tetrandrine (TET), a bisbenzylisoquinoline (BBI) alkaloid, is isolated from the plant

Indexed as

AnimalsApoptosisBenzylisoquinolinesBrainCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 3Cell Line, TumorGene Expression Regulation, NeoplasticGlioblastomaHumansMiceMyeloid Cell Leukemia Sequence 1 ProteinSignal TransductionStephania tetrandraXenograft Model Antitumor AssaysX-Linked Inhibitor of Apoptosis ProteinBenzylisoquinolinesCASP3 protein, humanCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 3CFLAR protein, humanMCL1 protein, humanMyeloid Cell Leukemia Sequence 1 ProteintetrandrineXIAP protein, humanX-Linked Inhibitor of Apoptosis Proteinhuman brain glioblastoma GBM 8401/luc2 cellsin vivonude miceTetrandrine (TET)xenograft tumor

Identifiers

PMID34885686
PMCPMC8659155
OpenAlexW3215190507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.