Evidence map›Paper›PMID 34885515›Full record

ArticleMaterials (Basel, Switzerland)2021

Synthesis and Characterization of Nanoporous Carbon Carriers for Losartan Potassium Delivery.

Aleksander Ejsmont, Anna Stasiłowicz-Krzemień, Dominika Ludowicz, Judyta Cielecka-Piontek, Joanna Goscianska

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Aleksander EjsmontFaculty of Chemistry, Department of Chemical Technology, Adam Mickiewicz University in Poznań, Uniwersytetu Poznańskiego 8, 61-614 Poznań, Poland.ORCID 0000-0002-1761-9411
Anna Stasiłowicz-KrzemieńFaculty of Pharmacy, Department of Pharmacognosy, Poznań University of Medical Sciences, Święcickiego 4, 61-781 Poznań, Poland.ORCID 0000-0001-5211-661X
Dominika LudowiczFaculty of Pharmacy, Department of Pharmacognosy, Poznań University of Medical Sciences, Święcickiego 4, 61-781 Poznań, Poland.
Judyta Cielecka-PiontekFaculty of Pharmacy, Department of Pharmacognosy, Poznań University of Medical Sciences, Święcickiego 4, 61-781 Poznań, Poland.ORCID 0000-0003-0891-5419
Joanna GoscianskaFaculty of Chemistry, Department of Chemical Technology, Adam Mickiewicz University in Poznań, Uniwersytetu Poznańskiego 8, 61-614 Poznań, Poland.ORCID 0000-0002-4202-652X
Poznan University of Medical Sciences · PLAdam Mickiewicz University in Poznań · PL

Funding

National Science Center 2016/23/D/NZ7/01347
6 · The paper itself

Abstract

Losartan potassium is most commonly used for the treatment of hypertension. In recent years, new applications of this drug have emerged, encouraging the design of novel nanoporous carriers for its adsorption and release. The purpose of this study was to synthesize ordered mesoporous carbon vehicles via a soft-templating method altered with the use of nitrogen precursors and via a hard-templating method followed by chitosan functionalization. As a result, the materials obtained differed in nitrogen content as well as in the number of total surface functional groups. The impact of the modification on the physicochemical properties of carbon carriers and their interaction with losartan potassium during adsorption and release processes was examined. The materials were characterized by various morphologies, specific surface areas (101-1180 m

Indexed as

adsorption of losartan potassiumchitosandrug liberationmesoporous carbon vehiclesnitrogen dopingsurface modification

Identifiers

PMID34885515
PMCPMC8658076
OpenAlexW3217110463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.