Evidence map›Paper›PMID 34885459›Full record

ReviewMaterials (Basel, Switzerland)2021

Fibroblasts Adhesion to Laser-Modified Titanium Surfaces-A Systematic Review.

Julia Kensy, Maciej Dobrzyński, Rafał Wiench, Kinga Grzech-Leśniak, Jacek Matys

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Effect of Titanium Dioxide (TiOMaterials (Basel, Switzerland) · 2026
    Review
  7. Article
  8. Naringenin-polyethylene glycol coating of titanium enhances biological seal-related functions of gingival fibroblasts under inflammatory challenge.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia KensyStudent Scientific Circle of Experimental Dentistry and Biomaterial Research, Faculty of Dentistry, Wroclaw Medical University, Bujwida 44, 50-345 Wroclaw, Poland.
Maciej DobrzyńskiDepartment of Pediatric Dentistry and Preclinical Dentistry, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.ORCID 0000-0003-2368-1534
Rafał WienchDepartment of Periodontal Diseases and Oral Mucosa Diseases, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Traugutta sq. 2, 41-800 Zabrze, Poland.ORCID 0000-0001-5673-7413
Kinga Grzech-LeśniakDepartment of Periodontics, School of Dentistry, Virginia Commonwealth University, Richmond, VA 23284, USA.ORCID 0000-0002-5700-4577
Jacek MatysLaser Laboratory at Dental Surgery Department, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveLaser treatment has been recently introduced in many fields of implant dentistry. The systematic review tried to address the question: "How does laser modification of titanium surface influence fibroblast adhesion?".

methodsAn electronic search of the PubMed and Scopus databases was performed. The following keywords were used: (laser) AND (fibroblast) AND (titanium) AND (implant OR disc) AND (proliferation OR adhesion). Initially, 136 studies were found. Ten studies met the inclusion criteria and were included in the review. All studies chosen to be included in the review were considered to have a low risk of bias.

resultsStudies included in the review varied with laser parameters or ways of observing fibroblast behavior. Studies showed that fibroblasts tend to take different shapes and create extensions on modified surfaces and that their metabolic activity is more intense. One study concentrated on laser application and showed that three-directional laser application is the most successful in terms of fibroblast adhesion. Studies which concentrated more on laser parameters showed that too low energy density (lower or equal to 0.75 J/cm

conclusionThe studies included in the review proved a positive effect of laser-modified titanium surfaces on fibroblast adhesion. However, the application of an appropriate laser energy dose is crucial.

Indexed as

CO2 laserdiscserbium laserimplantneodymium laser

Identifiers

PMID34885459
PMCPMC8658165

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.