Evidence map›Paper›PMID 34885261›Full record

ArticleMaterials (Basel, Switzerland)2021

Phase-Changing Glauber Salt Solution for Medical Applications in the 28-32 °C Interval.

Linus Olson, Carina Lothian, Ulrika Ådén, Hugo Lagercrantz, Nicola J Robertson, Fredrik Setterwall

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linus OlsonDepartment of Women's and Children's Health, Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0003-0046-6348
Carina LothianNeonatal Unit, Stockholm Söder Hospital, 11883 Stockholm, Sweden.
Ulrika ÅdénDepartment of Women's and Children's Health, Karolinska Institutet, 17177 Stockholm, Sweden.
Hugo LagercrantzDepartment of Women's and Children's Health, Karolinska Institutet, 17177 Stockholm, Sweden.
Nicola J RobertsonInstitute for Women's Health, University College London, London WC1E 6HU, UK.
Fredrik SetterwallDivision of Energy Processes, Chemical Engineering and Technology, Royal Institute of Technology, 10044 Stockholm, Sweden.

Funding

British Medical Association x.xStiftelsen Barncentrum zSwedish Research Council x.xVINNOVA
6 · The paper itself

Abstract

(1) Background: The field of medicine requires simple cooling materials. However, there is little knowledge documented about phase change materials (PCM) covering the range of 28 to 40 degrees Celsius, as needed for medical use. Induced mild hypothermia, started within 6 h after birth, is an emerging therapy for reducing death and severe disabilities in asphyxiated infants. Currently, this hypothermia is accomplished with equipment that needs a power source and a liquid supply. Neonatal cooling is more frequent in low-resource settings, where ~1 million deaths are caused by birth-asphyxia. (2) Methods: A simple and safe cooling method suitable for medical application is needed for the 28 to 37.5 °C window. (3) Results: Using empirical experiments in which the ingredients in Glauber salt were changed, we studied the effects of temperature on material in the indicated temperature range. The examination, in a controlled manner, of different mixtures of NaCl, Na

Indexed as

glauber salthypoxic ischemic encephalopathyneonatal asphyxiaphase change materialtherapeutic hypothermia

Identifiers

PMID34885261
PMCPMC8658730

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.