Evidence map›Paper›PMID 34885251›Full record

ReviewCancers2021

Vaccine Responses in Adult Hematopoietic Stem Cell Transplant Recipients: A Comprehensive Review.

Michelle Janssen, Anke Bruns, Jürgen Kuball, Reinier Raijmakers, Debbie van Baarle

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Comparison of Two High-Dose Versus Two Standard-Dose Influenza Vaccines in Adult Allogeneic Hematopoietic Cell Transplant Recipients.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Trial
  4. Experiences of racially, ethnically, sexual- and gender-minoritized adolescents and young adults with cancer in the Canadian health care system.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Recommendations on PCV20 vaccine in adults and at-risk populations.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Robust spike-specific CD4Frontiers in immunology · 2023
    Article
  15. Review
  16. Review
  17. Revaccination Response and Lack of Hepatitis B Reactivation After HCT for Sickle Cell Disease.Transplant infectious disease : an official journal of the Transplantation Society
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michelle JanssenDepartment of Infectious Diseases, UMC Utrecht, 3584 Utrecht, The Netherlands.ORCID 0000-0002-2710-1552
Anke BrunsDepartment of Infectious Diseases, UMC Utrecht, 3584 Utrecht, The Netherlands.
Jürgen KuballDepartment of Hematology, UMC Utrecht, 3584 Utrecht, The Netherlands.
Reinier RaijmakersDepartment of Hematology, UMC Utrecht, 3584 Utrecht, The Netherlands.
Debbie van BaarleCenter for Translational Immunology, UMC Utrecht, 3584 Utrecht, The Netherlands.
University Medical Center Utrecht · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Consensus on timing of post-hematopoietic stem cell transplantation (HSCT) vaccination is currently lacking and is therefore assessed in this review. PubMed was searched systematically for articles concerning vaccination post-HSCT and included a basis in predefined criteria. To enable comparison, data were extracted and tables were constructed per vaccine, displaying vaccine response as either seroprotection or seroconversion for allogeneic HSCT (alloHSCT) and autologous HSCT (autoHSCT) separately. A total of 33 studies were included with 1914 patients in total: 1654 alloHSCT recipients and 260 autoHSCT recipients. In alloHSCT recipients, influenza vaccine at 7-48 months post-transplant resulted in responses of 10-97%. After 12 months post-transplant, responses were >45%. Pneumococcal vaccination 3-25 months post-transplant resulted in responses of 43-99%, with the response increasing with time. Diphtheria, tetanus, pertussis, poliomyelitis and

Indexed as

hematopoietic stem cell transplantationvaccinationvaccine response

Identifiers

PMID34885251
PMCPMC8656479
OpenAlexW4200345203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.