ArticleCancers2021
Prevalence of Central Compartment Lymph Node Metastases in Papillary Thyroid Micro-Carcinoma: A Retrospective Evaluation of Predictive Preoperative Features.
Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Systematic review and meta-analysis of diagnostic accuracy of one-step nucleic acid amplification for lymph node metastases of papillary thyroid carcinoma.Langenbeck's archives of surgery · 2025Pooled it
- Preoperative predictors of occult central lymph node metastasis in clinically node-negative papillary thyroid carcinoma: a common data model-based retrospective cohort study.Annals of surgical treatment and research · 2026Article
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- Article
- Surgical Timing in Thyroid Cancer with Lateral Neck Metastases: Delayed Versus Contemporary Lateral Neck Dissection.Cancers · 2025Article
- Is conservative treatment always safe in unifocal clinically T1a/node-negative papillary thyroid carcinoma?World journal of surgery · 2025Article
- Central Neck Dissection in Papillary Thyroid Carcinoma: Benefits and Doubts in the Era of Thyroid Lobectomy.Biomedicines · 2024Article
- Two Rare Cases of Metastatic Occult Thyroid Carcinoma Without Primary Cancer in the Thyroid Gland.Cureus · 2024Article
- Carbon nanoparticles beneficial for prophylactic central compartment lymph node dissection in cN0 papillary thyroid carcinoma.Heliyon · 2024Article
- Long-term efficacy of lobectomy for stage T1 papillary thyroid carcinoma with varying degrees of lymph node metastasis.Frontiers in endocrinology · 2024Article
- Role of prophylactic central neck lymph node dissection for papillary thyroid carcinoma in the era of de-escalation.World journal of clinical oncology · 2023Review
- Prediction model of lymph node metastasis posterior to the right recurrent laryngeal nerve.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- A clinical and molecular pathology prediction model for central lymph node metastasis in cN0 papillary thyroid microcarcinoma.Frontiers in endocrinology · 2023Article
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Authors and funding
12 authors at 6 institutions in 1 country.
Funding
Abstract
Papillary thyroid micro-carcinomas are considered relatively indolent carcinomas, often occult and incidental, with good prognosis and favorable outcomes. Despite these findings, central lymph node metastases are common, and are related to a poor prognosis for the patient. We performed a retrospective analysis on patients treated with surgery for stage pT1a papillary thyroid micro-carcinomas. One hundred ninety-five patients were included in the analyses. The presence of central lymph node metastases was identified and studied. A multivariate analysis employing binary logistic regression was used to calculate adjusted odds ratios with 95% confidence intervals of possible central lymph node metastases risk factors. In the performed multivariate analysis, male gender, younger age, and histopathological characteristics, such as a tumor sub-capsular localization, were significantly associated with central lymph node metastases in pT1a patients. Central compartment lymph node metastases are present in a non-negligible number of cases in patients with papillary thyroid micro-carcinoma undergoing surgical resection. Studying these factors could be an effective tool for predicting patients' central lymph node metastases in papillary thyroid micro-carcinomas, defining a tailored surgical treatment in the future.
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