Evidence map›Paper›PMID 34885093›Full record

ArticleCancers2021

Organ Specific Copy Number Variations in Visceral Metastases of Human Melanoma.

Orsolya Papp, Viktória Doma, Jeovanis Gil, György Markó-Varga, Sarolta Kárpáti, József Tímár, Laura Vízkeleti

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Orsolya Papp2nd Department of Pathology, Semmelweis University, 1091 Budapest, Hungary.ORCID 0000-0002-0708-0010
Viktória Doma2nd Department of Pathology, Semmelweis University, 1091 Budapest, Hungary.
Jeovanis GilDivision of Oncology, Department of Clinical Sciences, Lund University, 221 84 Lund, Sweden.ORCID 0000-0003-3601-3893
György Markó-VargaClinical Protein Science & Imaging, Department of Biomedical Engineering, Lund University, 221 84 Lund, Sweden.
Sarolta KárpátiDepartment of Dermatology, Venerology and Dermato-Oncology, Semmelweis University, 1085 Budapest, Hungary.
József Tímár2nd Department of Pathology, Semmelweis University, 1091 Budapest, Hungary.
Laura Vízkeleti2nd Department of Pathology, Semmelweis University, 1091 Budapest, Hungary.ORCID 0000-0001-6870-3499
Semmelweis University · HULund University · SETokyo Medical University · JP

Funding

Hungarian Scientific Research Fund K135540National Research, Development and Innovation Fund NVKP-16-1-2016-004Research and Technology Innovation Fund KTIA_NAP_13- 2014-0021
6 · The paper itself

Abstract

Malignant melanoma is one of the most aggressive skin cancers with high potential of visceral dissemination. Since the information about melanoma genomics is mainly based on primary tumors and lymphatic or skin metastases, an autopsy-based visceral metastasis biobank was established. We used copy number variation arrays (

Indexed as

BRAF and NRAS mutant allele frequencyDDR deficiencydistant organ metastasisHGF/MET autocrine activationimmunogenic mimicry

Identifiers

PMID34885093
PMCPMC8657127
OpenAlexW3216948891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.