Evidence map›Paper›PMID 34885075›Full record

ReviewCancers2021

Novel Perspectives in Pseudomyxoma Peritonei Treatment.

Antonio Sommariva, Marco Tonello, Giulia Rigotto, Nayana Lazzari, Pierluigi Pilati, Maria Luisa Calabrò

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Effects of a clinic-referred telemedical intervention to improve exercise uptake during chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  3. Article
  4. Article
  5. Curiositas - Gastrointestinal Celebritas.The Ulster medical journal · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Antitumor effect of a small-molecule inhibitor of KRASExperimental hematology & oncology · 2023
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Antonio SommarivaSurgical Oncology of the Esophagus and Digestive Tract, Veneto Institute of Oncology IOV-IRCCS, 35100 Padua, Italy.ORCID 0000-0002-5764-5606
Marco TonelloSurgical Oncology of the Esophagus and Digestive Tract, Veneto Institute of Oncology IOV-IRCCS, 35100 Padua, Italy.ORCID 0000-0001-7190-2106
Giulia RigottoImmunology and Molecular Oncology, Veneto Institute of Oncology IOV-IRCCS, 35100 Padua, Italy.
Nayana LazzariImmunology and Molecular Oncology, Veneto Institute of Oncology IOV-IRCCS, 35100 Padua, Italy.
Pierluigi PilatiSurgical Oncology of the Esophagus and Digestive Tract, Veneto Institute of Oncology IOV-IRCCS, 35100 Padua, Italy.
Maria Luisa CalabròImmunology and Molecular Oncology, Veneto Institute of Oncology IOV-IRCCS, 35100 Padua, Italy.ORCID 0000-0001-9401-6182
Istituto Oncologico Veneto · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudomyxoma Peritonei (PMP) is an anatomo-clinical condition characterized by the implantation of neoplastic cells on peritoneal surfaces with the production of a large amount of mucin. The rarity of the disease precludes the evaluation of treatment strategies within randomized controlled trials. Cytoreductive Surgery (CRS) combined with Hyperthermic Intraperitoneal Chemotherapy (HIPEC) has proven to be the only therapeutic option with potential chances of cure and long-term disease control. The present review discusses the epidemiology, pathogenesis, clinical presentation and treatment of PMP, focusing on the molecular factors involved in tumor progression and mucin production that could be used, in the upcoming future, to improve patient selection for surgery and to expand the therapeutic armamentarium.

Indexed as

cytoreductive surgeryHIPECmucinperitoneal metastasesPseudomyxoma Peritonei

Identifiers

PMID34885075
PMCPMC8656832
OpenAlexW3217676001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.