Evidence map›Paper›PMID 34884989›Full record

ArticleCancers2021

The HROC-Xenobank-A High Quality Assured PDX Biobank of >100 Individual Colorectal Cancer Models.

Stephanie Matschos, Florian Bürtin, Said Kdimati, Mandy Radefeldt, Susann Krake, Friedrich Prall, Nadja Engel, Mathias Krohn, Bianca Micheel, Michael Kreutzer and 2 more

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Targeting metabolic dependencies to reverse chemoradiotherapy resistance in colorectal cancer.Journal of experimental & clinical cancer research : CR · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Stephanie MatschosClinic of General Surgery, Molecular Oncology and Immunotherapy, University Medicine Rostock, Schillingallee 69, 18057 Rostock, Germany.
Florian BürtinClinic of General Surgery, Molecular Oncology and Immunotherapy, University Medicine Rostock, Schillingallee 69, 18057 Rostock, Germany.
Said KdimatiClinic of General Surgery, Molecular Oncology and Immunotherapy, University Medicine Rostock, Schillingallee 69, 18057 Rostock, Germany.
Mandy RadefeldtCENTOGENE GmbH, 18055 Rostock, Germany.
Susann KrakeCENTOGENE GmbH, 18055 Rostock, Germany.
Friedrich PrallInstitute of Pathology, University Medicine Rostock, Strempelstraße 10, 18057 Rostock, Germany.
Nadja EngelDepartment of Oral, Maxillofacial and Plastic Surgery, University Medicine Rostock, Schillingallee 69, 18057 Rostock, Germany.ORCID 0000-0002-6362-9282
Mathias KrohnClinic of General Surgery, Molecular Oncology and Immunotherapy, University Medicine Rostock, Schillingallee 69, 18057 Rostock, Germany.
Bianca MicheelClinic of General Surgery, Molecular Oncology and Immunotherapy, University Medicine Rostock, Schillingallee 69, 18057 Rostock, Germany.
Michael KreutzerMedical Research Center, University Medicine Rostock, Schillingallee 69, 18057 Rostock, Germany.
Christina Susanne MullinsClinic of General Surgery, Molecular Oncology and Immunotherapy, University Medicine Rostock, Schillingallee 69, 18057 Rostock, Germany.ORCID 0000-0003-2296-2027
Michael LinnebacherClinic of General Surgery, Molecular Oncology and Immunotherapy, University Medicine Rostock, Schillingallee 69, 18057 Rostock, Germany.ORCID 0000-0001-8054-1402

Funding

State Mecklenburg-Vorpommern TBI-V-1-241-VBW-084
6 · The paper itself

Abstract

Based on our research group's large biobank of colorectal cancers (CRC), we here describe the ongoing activity of establishing a high quality assured PDX biobank for more than 100 individual CRC cases. This includes sufficient numbers of vitally frozen (

Indexed as

CRChistological examinationmutation analysisPDX model

Identifiers

PMID34884989
PMCPMC8656526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.