Evidence map›Paper›PMID 34884938›Full record

ArticleInternational journal of molecular sciences2021

Control of TRPM3 Ion Channels by Protein Kinase CK2-Mediated Phosphorylation in Pancreatic β-Cells of the Line INS-1.

Alexander Becker, Claudia Götz, Mathias Montenarh, Stephan E Philipp

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Roles of TRPM channels in glioma.Cancer biology & therapy · 2024
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alexander BeckerExperimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Building 46, D-66424 Homburg, Germany.
Claudia GötzMedical Biochemistry and Molecular Biology, Saarland University, Building 44, D-66424 Homburg, Germany.ORCID 0000-0001-7115-0485
Mathias MontenarhMedical Biochemistry and Molecular Biology, Saarland University, Building 44, D-66424 Homburg, Germany.ORCID 0000-0002-3777-382X
Stephan E PhilippExperimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Building 46, D-66424 Homburg, Germany.ORCID 0000-0003-1959-9167
Saarland University · DE

Funding

Deutsche Forschungsgemeinschaft CRC 894Dr. Rolf M. Schwiete Stiftung, Mannheim, Germany project Nr. 06/2015 to CG and MM and project Nr. 2020-006 to CGMedical Faculty of Saarland University HOMFOR
6 · The paper itself

Abstract

In pancreatic β-cells of the line INS-1, glucose uptake and metabolism induce the openings of Ca

Indexed as

AnimalsCalciumCasein Kinase IICell LineHEK293 CellsHumansInsulin-Secreting CellsMutationNaphthyridinesPhenazinesPhosphorylationPregnenoloneRatsRecombinant ProteinsTRPM Cation ChannelsCalciumCasein Kinase IINaphthyridinesPhenazinesPregnenolonepregnenolone sulfateRecombinant ProteinssilmitasertibTRPM3 protein, ratTRPM Cation Channelscalciumglucose-stimulated insulin release (GSIS)INS-1protein kinase CK2transient receptor potential M 3 channels (TRPM3)

Identifiers

PMID34884938
PMCPMC8658122
OpenAlexW4200030555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.