Evidence map›Paper›PMID 34884918›Full record

ArticleInternational journal of molecular sciences2021

Heat Shock Factor 1 Directly Regulates Postsynaptic Scaffolding PSD-95 in Aging and Huntington's Disease and Influences Striatal Synaptic Density.

Nicole Zarate, Taylor A Intihar, Dahyun Yu, Jacob Sawyer, Wei Tsai, Maha Syed, Luke Carlson, Rocio Gomez-Pastor

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

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  13. On the human health benefits of microalgal phytohormones: An explorativeComputational and structural biotechnology journal · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nicole ZarateDepartment of Neuroscience, School of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0003-4839-7783
Taylor A IntiharDepartment of Neuroscience, School of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Dahyun YuDepartment of Neuroscience, School of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Jacob SawyerDepartment of Neuroscience, School of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Wei TsaiDepartment of Neuroscience, School of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0001-6490-2212
Maha SyedDepartment of Neuroscience, School of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Luke CarlsonDepartment of Neuroscience, School of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Rocio Gomez-PastorDepartment of Neuroscience, School of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0003-1136-5462
University of Minnesota · US

Funding

Molecular mechanisms of synaptic dysfunction and cognitive decline in Huntington's diseaseR01NS110694 · NINDS · UNIVERSITY OF MINNESOTA · PI Rocio Gomez-Pastor · 2020 to 2026
$3.1M
Biomedical Research Awards for Interdisciplinary New Science (BRAINS) University of Minnesota N/ANINDS NIH HHS R01 NS110694NINDS NIH HHS R01NS110694
6 · The paper itself

Abstract

PSD-95 (

Indexed as

AgingAnimalsCorpus StriatumDisease Models, AnimalDisks Large Homolog 4 ProteinFemaleGene Expression RegulationHeat Shock Transcription FactorsHumansHuntington DiseaseMaleMiceMice, Inbred C57BLMice, Mutant StrainsProof of Concept StudySynapsesDisks Large Homolog 4 ProteinDLG4 protein, humanDlg4 protein, mouseHeat Shock Transcription FactorsHSF1 protein, humanHsf1 protein, mouseagingHSF1Huntington’s diseasePSD-95

Identifiers

PMID34884918
PMCPMC8657899
OpenAlexW4200547997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.